Evidence map›Paper›PMID 29169410›Full record

ArticleOncology research2018

miR-767-3p Inhibits Growth and Migration of Lung Adenocarcinoma Cells by Regulating CLDN18.

Yi Long Wan, Han Jue Dai, Wei Liu, Hai Tao Ma

Open access · hybridAbstract read
In one paragraph

Article in Oncology research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 37 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Yi Long WanDepartment of Thoracic Surgery, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, P.R. China.
Han Jue DaiDepartment of Oncology, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, P.R. China.
Wei LiuDepartment of Cardiology, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, P.R. China.
Hai Tao MaDepartment of Thoracic Surgery, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, P.R. China.
First Affiliated Hospital of Soochow University · CNSoochow University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Claudin18 (CLDN18) is necessary for intercellular junctions and is reported to be involved in cell migration and metastasis, making it like an oncogene in various cancer types. However, the biological function and regulatory mechanisms of CLDN18 in lung adenocarcinoma are not yet clear. In this study, we found downregulation of miR-767-3p and upregulation of

Indexed as

AdenocarcinomaAnimalsCell Line, TumorCell MovementCell ProliferationClaudinsGene Expression Regulation, NeoplasticHumansLung NeoplasmsMiceMicroRNAsXenograft Model Antitumor AssaysClaudinsCLDN18 protein, humanMicroRNAsMIRN-767 microRNA, human

Identifiers

PMID29169410
PMCPMC7844711
OpenAlexW2770352187

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.