Evidence map›Paper›PMID 29169376›Full record

ArticleBMC research notes2017

The mediating factors in the relationship between lower urinary tract symptoms and health-related quality of life.

Weng-Yee Chin, Edmond P H Choi, Eric Y F Wan, Cindy L K Lam

Abstract read
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In one paragraph

Article in BMC research notes, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Effects ofFood science & nutrition · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Weng-Yee ChinDepartment of Family Medicine and Primary Care, University of Hong Kong, 3/F., 161 Main Street, Ap Lei Chau Clinic, Ap Lei Chau, Hong Kong. chinwy@hku.hk.
Edmond P H ChoiDepartment of Family Medicine and Primary Care, University of Hong Kong, 3/F., 161 Main Street, Ap Lei Chau Clinic, Ap Lei Chau, Hong Kong. h0714919@connect.hku.hk.
Eric Y F WanDepartment of Family Medicine and Primary Care, University of Hong Kong, 3/F., 161 Main Street, Ap Lei Chau Clinic, Ap Lei Chau, Hong Kong.
Cindy L K LamDepartment of Family Medicine and Primary Care, University of Hong Kong, 3/F., 161 Main Street, Ap Lei Chau Clinic, Ap Lei Chau, Hong Kong.

Funding

Small Project Funding, Committee on Research and Conference Grants of the University of Hong Kong 201209176016the Health and Health Services Research Fund, Food and Health Bureau, HKSAR Commissioned Research on Enhanced Primary Care Study EPC-HKU-2
6 · The paper itself

Abstract

objectivesAn earlier study found that mental health partially mediates the relationship between lower urinary tract symptoms (LUTS) severity and health-related quality of life (HRQOL). In other words, LUTS adversely affects mental health, which in turn adversely affects HRQOL. A major limitation of the previous study was its cross-sectional design. The aim of this study is to evaluate whether changes in mental health mediated the association between changes in the severity of LUTS and changes in HRQOL over 24 months by using Baron and Kenny's regression procedure and Preacher and Hayes's bootstrapping method.

resultsWe found that changes in mental health were a mediator in the relationship between the change of LUTS severity and the change of LUTS-specific HRQOL. Changes in LUTS severity lead to changes in mental health, which in turn affects the change of LUTS-specific HRQOL. It was observed however that changes in mental health did not mediate the relationship between the change of LUTS severity and the change of the physical aspects of generic HRQOL. These findings suggest that in order to optimize LUTS-specific HRQOL, both LUTS severity and mental health may need to be addressed concurrently.

Indexed as

AdolescentAdultAgedAnxietyDepressionFemaleFollow-Up StudiesHumansLower Urinary Tract SymptomsMaleMiddle AgedQuality of LifeYoung AdultAnxietyDepressionLower urinary tract symptomsMental healthNursingPrimary careQuality of lifeStress

Identifiers

PMID29169376
PMCPMC5701359

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.