Evidence map›Paper›PMID 29169369›Full record

ArticleBMC complementary and alternative medicine2017

In vivo screening and evaluation of four herbs against MRSA infections.

Najma Arshad, Arifa Mehreen, Iram Liaqat, Muhammad Arshad, Humera Afrasiab

Open access · goldAbstract read
In one paragraph

Article in BMC complementary and alternative medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.3field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
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  4. Review
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  6. Saudi journal of biological sciences · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Najma ArshadDepartment of Zoology, University of the Punjab, Lahore, Punjab, Pakistan. najmaarshad@gmail.com.
Arifa MehreenDepartment of Zoology, University of the Punjab, Lahore, Punjab, Pakistan.
Iram LiaqatDepartment of Zoology, Government College University, Lahore, Punjab, Pakistan.
Muhammad ArshadDepartment of Zoology, University of Education, Lahore, Punjab, Pakistan.
Humera AfrasiabDepartment of Botany, University of the Punjab, Lahore, Punjab, Pakistan.
University of the Punjab · PKGovernment College University, Lahore · PKUniversity of Education · PK

Funding

Higher Education Commission, Pakistan 106-1813-BM6-143
6 · The paper itself

Abstract

backgroundRecently, we reported high in vitro antibacterial efficacy of Althaea officinalis, Ziziphus jujuba, Cordia latifolia and Thymus vulgaris out of a total 21 plants against wide range of bacteria including MRSA. This study was therefore, designed to confirm efficacy of these four herbs against MRSA in an animal model.

methodsA pilot study was conducted to establish the dose of S. aureus (KY698020) required to induce clinical infection. Afterword, in main trial, efficacy of aforementioned plant extracts on the course of sore throat was checked by evaluating general health, gross lesion score, bacterial load and hematology in mice.

resultsPilot study revealed that 40 μl dose of 10

conclusionThis is first report confirming in vivo anti-MRSA potential of C. latifolia and T. vulgaris and highlight the need to explore bioactive constituents of these plants. Moreover, previously reported in vitro antibacterial efficiency of A. officinalis could not be validated in current study.

Indexed as

AlthaeaAnimalsBacterial LoadCordiaDisease Models, AnimalHematologic TestsMethicillin-Resistant Staphylococcus aureusMicePilot ProjectsPlant ExtractsStaphylococcal InfectionsThymus PlantTissue DistributionZiziphusPlant ExtractsA. officinalisBacterial loadC. latifoliaHaematologyin vivoLesion scoreS. aureusT. vulgarisZ. jujuba

Identifiers

PMID29169369
PMCPMC5701375
OpenAlexW2770959518

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.