ArticleBMC evolutionary biology2017
Evidence of high-altitude adaptation in the glyptosternoid fish, Creteuchiloglanis macropterus from the Nujiang River obtained through transcriptome analysis.
Article in BMC evolutionary biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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10 citing papers in PubMed.
- Developmental plasticity of the cardiovascular system in oviparous vertebrates: effects of chronic hypoxia and interactive stressors in the context of climate change.The Journal of experimental biology · 2024Review
- PacBio Full-Length Transcriptome of a TetraploidAnimals : an open access journal from MDPI · 2023Article
- The relevance of genetic structure in ecotype designation and conservation management.Evolutionary applications · 2022Article
- Genome and population evolution and environmental adaptation ofZoological research · 2021Article
- Targeting the Mild-Hypoxia Driving Force for Metabolic and Muscle Transcriptional Reprogramming of Gilthead Sea Bream (Biology · 2021Article
- Genomic Signature of Shifts in Selection and Alkaline Adaptation in Highland Fish.Genome biology and evolution · 2021Article
- Comprehensive Transcriptome Analysis Reveals Insights into Phylogeny and Positively Selected Genes ofAnimals : an open access journal from MDPI · 2020Article
- Transcriptome analysis of the growth performance of hybrid mandarin fish after food conversion.PloS one · 2020Article
- Analysis of Multiplicity of Hypoxia-Inducible Factors in the Evolution ofFrontiers in genetics · 2020Article
- Transcriptome Analysis Provides Insights Into the Adaptive Responses to Hypoxia of a Schizothoracine Fish (Frontiers in physiology · 2018Article
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3 authors.
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Abstract
backgroundOrganisms living at high altitudes face low oxygen and temperature conditions; thus, the genetic mechanisms underlying the adaptations in these organisms merit investigation. The glyptosternoid fish, Creteuchiloglanis macropterus mainly inhabits regions with gradual increases in altitudes along the Nujiang River and might serve as an appropriate evolutionary model for detecting adaptation processes in environments with altitude changes.
resultsWe constructed eleven RNA-sequencing (RNA-seq) libraries of C. macropterus collected from five locations at different altitudes to identify the genetic signatures of high-altitude adaptation. The comparative genomic analysis indicated that C. macropterus has an accelerated evolutionary rate compared with that of fishes in the lowland, and fishes at higher altitudes might evolve faster. Functional enrichment analysis of the fast-evolving and positively selected genes, differentially expressed genes and highly expressed genes, showed that these genes were involved in many functions related to energy metabolism and hypoxia.
conclusionsOur study provides evidence of high-altitude adaptation in C. macropterus, and the detected adaptive genes might be a resource for future investigations of adaptations to high-altitude environments in other fishes.
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