Evidence map›Paper›PMID 29168892›Full record

ArticleJournal of neurochemistry2018

Functional properties of dopamine transporter oligomers after copper linking.

Juan Zhen, Maarten E A Reith

Open access · bronzeAbstract read
In one paragraph

Article in Journal of neurochemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 20 citations in OpenAlex.

  1. Transient Suppression of Dopamine Transporter Palmitoylation by Methamphetamine: Implications for Transport Regulation.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Article
  2. Article
  3. Oligomerization of Monoamine Transporters.Sub-cellular biochemistry · 2024
    Review
  4. Review
  5. Article
  6. Review
  7. SLC6 transporter oligomerization.Journal of neurochemistry · 2021
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Juan ZhenDepartment of Psychiatry, New York University School of Medicine, New York City, New York, USA.ORCID 0000-0002-6111-9692
Maarten E A ReithDepartment of Psychiatry, New York University School of Medicine, New York City, New York, USA.
New York University · US

Funding

Dopamine Transporters: Mechanisms of Ligand InteractionR01DA019676 · NIDA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI REITH, MAARTEN E · 2006 to 2016
$2.9M
NIDA NIH HHS R01 DA019676
6 · The paper itself

Abstract

Although it is universally accepted that dopamine transporters (DATs) exist in monomers, dimers and tetramers (i.e. dimers of dimers), it is not known whether the oligomeric organization of DAT is a prerequisite for its ability to take up dopamine (DA), or whether each DAT protomer, the subunit of quaternary structure, functions independently in terms of DA translocation. In this study, copper phenanthroline (CuP) was used to selectively target surface DAT: increasing concentrations of CuP gradually cross-linked natural DAT dimers in LLC-PK

Indexed as

AnimalsBiotinylationCocaineCross-Linking ReagentsDopamine Plasma Membrane Transport ProteinsDopamine Uptake InhibitorsHEK293 CellsHumansKineticsLLC-PK1 CellsPhenanthrolinesProtein BindingSwineTropanes1,10-phenanthroline2beta-carbomethoxy-3beta-(4-(11C)fluorophenyl)tropaneCocaineCross-Linking ReagentsDopamine Plasma Membrane Transport ProteinsDopamine Uptake InhibitorsPhenanthrolinesTropanesbindingcocaine analogcross-linkingdopamine transporter oligomersfunctional activityprotomers

Identifiers

PMID29168892
PMCPMC5760346
OpenAlexW2769582909

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.