Evidence map›Paper›PMID 29168738›Full record

ReviewToxins2017

Therapeutic Potential of Cholera Toxin B Subunit for the Treatment of Inflammatory Diseases of the Mucosa.

Joshua M Royal, Nobuyuki Matoba

Open access · goldAbstract readReview
In one paragraph

Review in Toxins, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. The diverse landscape of AB5-type toxins.Engineering microbiology · 2023
    Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. A modified cholera toxin B subunit containing an ER retention motif enhances colon epithelial repairFASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2019
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Protection AgainstFrontiers in immunology · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Joshua M RoyalDepartment of Pharmacology and Toxicology, University of Louisville School of Medicine, Louisville, KY 40202, USA. joshua.royal@louisville.edu.
Nobuyuki MatobaDepartment of Pharmacology and Toxicology, University of Louisville School of Medicine, Louisville, KY 40202, USA. n.matoba@louisville.edu.
University of Louisville · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cholera toxin B subunit (CTB) is a mucosal immunomodulatory protein that induces robust mucosal and systemic antibody responses. This well-known biological activity has been exploited in cholera prevention (as a component of Dukoral

Indexed as

AnimalsAnti-Inflammatory AgentsCholera ToxinEpithelial CellsHumansImmunologic FactorsIntestinal MucosaMolecular StructureAnti-Inflammatory AgentsCholera ToxinImmunologic Factorsanti-inflammatorycholera toxin B subunitGM1 gangliosideimmunomodulationmucosal immunityretrograde trafficking

Identifiers

PMID29168738
PMCPMC5744099
OpenAlexW2768710519

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.