ArticleeLife2017
Zfp281 is essential for mouse epiblast maturation through transcriptional and epigenetic control of Nodal signaling.
Article in eLife, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
27 citing papers in PubMed.
- PCBP1 orchestrates amino acid metabolism burst during the naïve-to-primed pluripotency transition.Stem cell reports · 2026Article
- Mechanisms coordinating exit from the stem cell state in mammals.Genes & development · 2026Review
- Enforced ZFP281 expression delays breast cancer initiation and can provide lifelong protection against breast cancer metastasis.bioRxiv : the preprint server for biology · 2026Article
- Seasonal Changes in the Seminal Plasma Proteome of the Crab-Eating Fox (Journal of proteome research · 2026Article
- A conserved function of EZH2-PRC2 in repression of primitive endoderm fate in mouse and human pluripotent cells.Stem cell reports · 2025Article
- H3K27ac Is Essential for Human Naive Pluripotency Modulated by m6A-Driven EP300 Expression.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- ETV4 and ETV5 orchestrate FGF-mediated lineage specification and epiblast maturation during early mouse development.Development (Cambridge, England) · 2025Article
- Capture primed pluripotency in guinea pig.Stem cell reports · 2025Article
- BRD8 Guards the Pluripotent State by Sensing and Maintaining Histone Acetylation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- ETV4 and ETV5 Orchestrate FGF-Mediated Lineage Specification and Epiblast Maturation during Early Mouse Development.bioRxiv : the preprint server for biology · 2024Article
- Single-cell lineage capture across genomic modalities with CellTag-multi reveals fate-specific gene regulatory changes.Nature biotechnology · 2024Article
- ZFP281 controls transcriptional and epigenetic changes promoting mouse pluripotent state transitions via DNMT3 and TET1.Developmental cell · 2024Article
- Zfp296 knockout enhances chromatin accessibility and induces a unique state of pluripotency in embryonic stem cells.Communications biology · 2023Article
- Inhibition of Annexin A10 Contributes to ZNF281 Mediated Aggressiveness of Hepatocellular Carcinoma.Journal of hepatocellular carcinoma · 2023Article
- Transcription factor antagonism regulates heterogeneity in embryonic stem cell states.Molecular cell · 2022Article
- ZFP281 drives a mesenchymal-like dormancy program in early disseminated breast cancer cells that prevents metastatic outgrowth in the lung.Nature cancer · 2022Article
- Stepwise pluripotency transitions in mouse stem cells.EMBO reports · 2022Review
- ZFP281-BRCA2 prevents R-loop accumulation during DNA replication.Nature communications · 2022Article
- A TET1-PSPC1-Neat1 molecular axis modulates PRC2 functions in controlling stem cell bivalency.Cell reports · 2022Article
- Zfp281 is essential for epiblast maturation through a cell autonomous effect.Journal of genetics and genomics = Yi chuan xue bao · 2022Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
Pluripotency is defined by a cell's potential to differentiate into any somatic cell type. How pluripotency is transited during embryo implantation, followed by cell lineage specification and establishment of the basic body plan, is poorly understood. Here we report the transcription factor Zfp281 functions in the exit from naive pluripotency occurring coincident with pre-to-post-implantation mouse embryonic development. By characterizing
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.