Evidence map›Paper›PMID 29168339›Full record

ArticleCancer medicine2018

Prognostic value of PD-L1 expression in combination with CD8

Hui Yang, Jinpeng Shi, Dongmei Lin, Xuefei Li, Chao Zhao, Qi Wang, Limin Zhang, Tao Jiang, Sha Zhao, Xiaozhen Liu and 4 more

Registry-linked trialAbstract read
In one paragraph

Article in Cancer medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05185505 (Atezolizumab and Bevacizumab Pre-Liver Transplantation for Patients With Hepatocellular Carcinoma Beyond Milan Criteria), which is not on this map. Cited by 36 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05185505 phase4recruitingnot on this mapstarted 2023, after this paper: background citation

Atezolizumab and Bevacizumab Pre-Liver Transplantation for Patients With Hepatocellular Carcinoma Beyond Milan Criteria: A Feasibility Study

TypeinterventionalSponsorThe Methodist Hospital Research InstituteRan2023 to 2027Enrolled24ConditionsHepatocellular Carcinoma, Hepatocellular CancerArmsAtezolizumab, Bevacizumab
3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
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  7. Biomedicines · 2025
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  8. Article
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  12. Review
  13. Review
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  15. Prognostic significance of PD-L1 expression and CD8Journal of thoracic disease · 2022
    Article
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  17. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Hui YangDepartment of Medical Oncology, Shanghai Pulmonary Hospital & Thoracic Cancer Institute, Tongji University School of Medicine, Shanghai, 200433, China.
Jinpeng ShiDepartment of Medical Oncology, Shanghai Pulmonary Hospital & Thoracic Cancer Institute, Tongji University School of Medicine, Shanghai, 200433, China.
Dongmei LinKey Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital and Institute, Beijing, 100142, China.
Xuefei LiDepartment of Lung Cancer and Immunology, Shanghai Pulmonary Hospital & Thoracic Cancer Institute, Tongji University School of Medicine, Shanghai, 200433, China.
Chao ZhaoDepartment of Lung Cancer and Immunology, Shanghai Pulmonary Hospital & Thoracic Cancer Institute, Tongji University School of Medicine, Shanghai, 200433, China.
Qi WangDepartment of Pathology, Yancheng Third People's Hospital, Yancheng, 224001, China.
Limin ZhangDepartment of Medical Oncology, Shanghai Pulmonary Hospital & Thoracic Cancer Institute, Tongji University School of Medicine, Shanghai, 200433, China.ORCID 0000-0002-5605-7204
Tao JiangDepartment of Medical Oncology, Shanghai Pulmonary Hospital & Thoracic Cancer Institute, Tongji University School of Medicine, Shanghai, 200433, China.
Sha ZhaoDepartment of Medical Oncology, Shanghai Pulmonary Hospital & Thoracic Cancer Institute, Tongji University School of Medicine, Shanghai, 200433, China.
Xiaozhen LiuDepartment of Medical Oncology, Shanghai Pulmonary Hospital & Thoracic Cancer Institute, Tongji University School of Medicine, Shanghai, 200433, China.
Yijun JiaDepartment of Medical Oncology, Shanghai Pulmonary Hospital & Thoracic Cancer Institute, Tongji University School of Medicine, Shanghai, 200433, China.
Yajun ZhangDepartment of Thoracic Surgery, Yancheng Third People's Hospital, Yancheng, 224001, China.
Weijing CaiDepartment of Medical Oncology, Shanghai Pulmonary Hospital & Thoracic Cancer Institute, Tongji University School of Medicine, Shanghai, 200433, China.
Caicun ZhouDepartment of Medical Oncology, Shanghai Pulmonary Hospital & Thoracic Cancer Institute, Tongji University School of Medicine, Shanghai, 200433, China.ORCID 0000-0003-0073-6619

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To investigate the prognostic value of PD-L1 expression combined with CD8

Indexed as

AdultAgedAsian PeopleB7-H1 AntigenBiomarkers, TumorCarcinoma, Non-Small-Cell LungCD8-Positive T-LymphocytesDisease-Free SurvivalFemaleHumansKaplan-Meier EstimateLung NeoplasmsLymphatic MetastasisLymphocyte CountLymphocytes, Tumor-InfiltratingMaleB7-H1 AntigenBiomarkers, TumorCD274 protein, humanCD8non-small cell lung cancerprognosisprogrammed cell death ligand-1tumor infiltrating lymphocytes

Identifiers

PMID29168339
PMCPMC5773962

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.