Evidence map›Paper›PMID 29168158›Full record

ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2019

Assessment of attenuation correction for myocardial PET imaging using combined PET/MRI.

Martin Lyngby Lassen, Sazan Rasul, Dietrich Beitzke, Marie-Elisabeth Stelzmüller, Jacobo Cal-Gonzalez, Marcus Hacker, Thomas Beyer

Abstract read
In one paragraph

Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed.

  1. Trial
  2. Quantitative imaging in medicine and surgery · 2026
    Article
  3. Review
  4. Article
  5. International EANM-SNMMI-ISMRM consensus recommendation for PET/MRI in oncology.European journal of nuclear medicine and molecular imaging · 2023
    Article
  6. Review
  7. Left ventricular function and volumes from gated [Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023
    Article
  8. Article
  9. Article
  10. Advances in cardiac PET/MR imaging: Facilitating cutting-edge structural and biological phenotyping of the cardiovascular system.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021
    Article
  11. CardiovascularJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021
    Article
  12. Assessing the qualitative and quantitative impacts of simple two-class vs multiple tissue-class MR-based attenuation correction for cardiac PET/MR.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021
    Article
  13. Cardiac PET/MR: Are sophisticated attenuation correction techniques necessary for clinical routine assessments?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021
    Article
  14. Review of cardiovascular imaging in the Journal of Nuclear Cardiology 2020: positron emission tomography, computed tomography, and magnetic resonance.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021
    Review
  15. Article
  16. Myocardial creep-induced misalignment artifacts in PET/MR myocardial perfusion imaging.European journal of nuclear medicine and molecular imaging · 2021
    Article
  17. Splenic switch-off as a predictor for coronary adenosine response: validation against 13N-ammonia during co-injection myocardial perfusion imaging on a hybrid PET/CMR scanner.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2021
    Article
  18. Attenuation correction for human PET/MRI studies.Physics in medicine and biology · 2020
    Article
  19. [A review on cardiac positron emission tomography/magnetic resonance imaging in diagnosis of cardivascular diseases].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2020
    Review
  20. PET-derived bone information from 18F-sodium fluoride: A perfect match for whole-body PET/MR attenuation correction?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Martin Lyngby LassenQIMP Group, Center for Medical Physics and Biomedical Engineering, General Hospital Vienna, Medical University of Vienna, 1090, Vienna, Austria. martin.lassen@meduniwien.ac.at.
Sazan RasulDivision of Nuclear Medicine, Department of Biomedical Engineering and Image-guided Therapy, Medical University of Vienna, Vienna, Austria.
Dietrich BeitzkeDivision of Cardiovascular and Interventional Radiology, Department of Biomedical Engineering and Image-guided Therapy, Medical University of Vienna, Vienna, Austria.
Marie-Elisabeth StelzmüllerDepartment of Cardiac Surgery, Medical University of Vienna, Vienna, Austria.
Jacobo Cal-GonzalezQIMP Group, Center for Medical Physics and Biomedical Engineering, General Hospital Vienna, Medical University of Vienna, 1090, Vienna, Austria.
Marcus HackerDivision of Nuclear Medicine, Department of Biomedical Engineering and Image-guided Therapy, Medical University of Vienna, Vienna, Austria.
Thomas BeyerQIMP Group, Center for Medical Physics and Biomedical Engineering, General Hospital Vienna, Medical University of Vienna, 1090, Vienna, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the frequency of artifacts in MR-based attenuation correction (AC) maps and their impact on the quantitative accuracy of PET-based flow and metabolism measurements in a cohort of consecutive heart failure patients undergoing combined PET/MR imaging.

methodsMyocardial viability studies were performed in 20 patients following a dual-tracer protocol involving the assessment of myocardial perfusion (

resultsAverage respiratory misalignment of (7 ± 4) mm of the PET-emission data and the AC maps was observed in 18 (90%) patients. Substantial changes in the lung volumes of the AC maps were observed in the test-retest analysis (ratio: 1.0 ± 0.2, range: 0.8-1.4). Susceptibility artifacts were observed in 10 (50%) patients, while six (30%) patients had TI artifacts. Average differences of 14 ± 10% were observed for PET images reconstructed with the artifactual AC maps. The combined artifact effects caused false-positive findings in three (15%) patients.

conclusionStandard DIXON-AC maps must be examined carefully for artifacts and misalignment effects prior to AC correction of cardiac PET/MRI studies in order to avoid misinterpretation of biased perfusion and metabolism readings from the PET data.

Indexed as

Magnetic Resonance ImagingPositron-Emission TomographyAgedAged, 80 and overAlgorithmsArtifactsFemaleFluorodeoxyglucose F18HeartHeart FailureHumansImage Processing, Computer-AssistedMaleMiddle AgedMultimodal ImagingMyocardial Perfusion ImagingFluorodeoxyglucose F18artifactsAttenuation correctioncardiac PETPET/MR

Identifiers

PMID29168158
PMCPMC6660490

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.