Evidence map›Paper›PMID 29168040›Full record

ArticleSleep & breathing = Schlaf & Atmung2018

The utility of home sleep apnea tests in patients with low versus high pre-test probability for moderate to severe OSA.

Cathy A Goldstein, Hala Karnib, Katherine Williams, Zunaira Virk, Afifa Shamim-Uzzaman

Abstract read
PubMed Publisher
In one paragraph

Article in Sleep & breathing = Schlaf & Atmung, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Respiratory event index underestimates severity of sleep apnea compared to apnea-hypopnea index.Sleep advances : a journal of the Sleep Research Society · 2024
    Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Cathy A GoldsteinSleep Disorders Center, Department of Neurology, University of Michigan, 1500 East Medical Center Drive, Med Inn C728, Ann Arbor, MI, 48109, USA. cathygo@med.umich.edu.ORCID http://orcid.org/0000-0003-1777-0274
Hala KarnibDivision of Pulmonary, Critical Care, and Sleep Disorders Medicine, Department of Medicine, University of Louisville School of Medicine, Louisville, KY, USA.
Katherine WilliamsDivision of Thoracic Diseases and Critical Care, Mayo Clinic Arizona, Rochester, USA.
Zunaira VirkSleep Disorders Center, Department of Neurology, University of Michigan, 1500 East Medical Center Drive, Med Inn C728, Ann Arbor, MI, 48109, USA.
Afifa Shamim-UzzamanSleep Disorders Center, Department of Neurology, University of Michigan, 1500 East Medical Center Drive, Med Inn C728, Ann Arbor, MI, 48109, USA.
University of Michigan · USMayo Clinic in Arizona · USUniversity of Louisville · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeHome sleep apnea tests (HSATs) are an alternative to attended polysomnograms (PSGs) when the pre-test probability for moderate to severe OSA is high. However, insurers often mandate use anytime OSA is suspected regardless of the pre-test probability. Our objective was to determine the ability of HSATs to rule in OSA when the pre-test probability of an apnea hypopnea index (AHI) in the moderate to severe range is low.

methodsPatients who underwent HSATs were characterized as low or high pre-test probability based on the presence of two symptoms of the STOP instrument plus either BMI > 35 or male gender. The odds of HSAT diagnostic for OSA dependent on pre-test probability was calculated. Stepwise selection determined predictors of non-diagnostic HSAT. As PSG is performed after HSATs that do not confirm OSA, false negative results were assessed.

resultsAmong 196 individuals, pre-test probability was low in 74 (38%) and high in 122 (62%). A lower percentage of individuals with a low versus high pre-test probability for moderate to severe OSA had HSAT results that confirmed OSA (61 versus 84%, p = 0.0002) resulting in an odds ratio (OR) of 0.29 for confirmatory HSAT in the low pre-test probability group (95% CI [0.146, 0.563]). Multivariate logistic regression demonstrated that age ≤ 50 (OR 3.10 [1.24-7.73]), female gender (OR 3.58[1.50-8.66]), non-enlarged neck circumference (OR 11.50 [2.50-52.93]), and the absence of loud snoring (OR 3.47 [1.30-9.25]) best predicted non-diagnostic HSAT. OSA was diagnosed by PSG in 54% of individuals with negative HSAT which was similar in both pre-test probability groups.

conclusionHSATs should be reserved for individuals with high pre-test probability for moderate to severe disease as opposed to any individual with suspected OSA.

Indexed as

HousingAdultFemaleHumansMaleMiddle AgedPolysomnographyProbabilityRetrospective StudiesSleep Apnea SyndromesHome sleep apnea testObstructive sleep apneaPolysomnogramPre-test probability

Identifiers

PMID29168040
OpenAlexW2768997667

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.