ArticleEuropean journal of nuclear medicine and molecular imaging2018
Preoperative prediction of microvascular invasion of hepatocellular carcinoma using
Article in European journal of nuclear medicine and molecular imaging, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 2 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
43 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Diagnostic performance of FDG PET/CT radiomics in predicting microvascular invasion in hepatocellular carcinoma compared to conventional metabolic parameters: a systematic review and meta-analysis.Annals of nuclear medicine · 2025Pooled it
- Preoperative Prediction Power of Imaging Methods for Microvascular Invasion in Hepatocellular Carcinoma: A Systemic Review and Meta-Analysis.Frontiers in oncology · 2020Pooled it
- Clinical Robustness of FDG-PET/CT Quantitative Metrics Post-Harmonization in a Multicenter, Cross-Scanner Setting.Tomography (Ann Arbor, Mich.) · 2026Article
- Correlation between 18 F-FDG PET/CT, Gd-EOB-DTPA MRI combined with laboratory parameters and microvascular invasion, and the potential of nomogram to predict microvascular invasion of hepatocellular carcinoma before liver transplantation.Nuclear medicine communications · 2026Article
- Correlation study of 18F-FDG PET/CT metabolic parameters, heterogeneity index, and microvascular invasion, and its nomogram potential in predicting microvascular invasion in liver cancer before liver transplantation.Nuclear medicine communications · 2025Article
- Prognostic and diagnostic value of [European radiology · 2025Article
- Chinese expert consensus on the diagnosis and treatment of hepatocellular carcinoma with microvascular invasion (2024 edition).Hepatobiliary surgery and nutrition · 2025Review
- A Machine Learning-Based Clustering Using Radiomics of F-18 Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography for the Prediction of Prognosis in Patients with Intrahepatic Cholangiocarcinoma.Diagnostics (Basel, Switzerland) · 2024Article
- Preoperative prediction of microvascular invasion: new insights into personalized therapy for early-stage hepatocellular carcinoma.Quantitative imaging in medicine and surgery · 2024Review
- The potential ofAbdominal radiology (New York) · 2024Article
- Multi-transcriptomics analysis of microvascular invasion-related malignant cells and development of a machine learning-based prognostic model in hepatocellular carcinoma.Frontiers in immunology · 2024Article
- Head-to-head comparison ofCancer imaging : the official publication of the International Cancer Imaging Society · 2023Article
- Analysis of Sonazoid contrast-enhanced ultrasound for predicting the risk of microvascular invasion in hepatocellular carcinoma: a prospective multicenter study.European radiology · 2023Article
- Combined early dynamicAbdominal radiology (New York) · 2023Article
- Predicting Outcome after Percutaneous Ablation for Early-Stage Hepatocellular Carcinoma Using Various Imaging Modalities.Diagnostics (Basel, Switzerland) · 2023Review
- Article
- [Prediction of microvascular invasion in hepatocellular carcinoma with magnetic resonance imaging using models combining deep attention mechanism with clinical features].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2023Article
- [Research progress of radiomics in the evaluation of microvascular invasion in hepatocellular carcinoma].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2023Article
- Preoperative prediction of lymphovascular invasion of colorectal cancer by radiomics based on 18F-FDG PET-CT and clinical factors.Frontiers in radiology · 2023Article
- Tumor metabolism derived fromQuantitative imaging in medicine and surgery · 2023Article
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
purposeThe aim of this study was to assess the potential of tumor
methodsOne hundred and fifty-eight patients diagnosed with Barcelona Clinic Liver Cancer stages 0 or A HCC (median age, 57 years; interquartile range, 50-64 years) who underwent
resultsMVI was present in 76 of 158 patients with HCCs (48.1%). Multivariable logistic regression analysis revealed that TLR, serum alpha-fetoprotein (AFP) level, and tumor size were significantly associated with the presence of MVI (P < 0.001). Multinodularity was not significantly associated with MVI (P = 0.563). The area under the ROC curve (AUC) for predicting the presence of MVI was best with TLR (AUC = 0.704), followed by tumor size (AUC = 0.685) and AFP (AUC = 0.670). We were able to build an improved prediction model combining TLR, tumor size, and AFP by using multivariable logistic regression modeling (AUC = 0.756).
conclusionsTumor FDG avidity measured by TLR on FDG PET/CT is a preoperative imaging biomarker for the prediction of MVI in patients with HCC.
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