ArticleIranian journal of public health2017
Guiding Effect of Serum Procalcitonin (PCT) on the Antibiotic Application to Patients with Sepsis.
Article in Iranian journal of public health, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 4 syntheses or guidelines pooled it, 13 citations in OpenAlex.
- Pooled it
- Efficacy and Safety of Procalcitonin-Guided Antibiotic Therapy versus Standard of Care for Sepsis: A Systematic Review and Meta-Analysis.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2026Pooled it
- [S3 guideline on sepsis-prevention, diagnosis, therapy, and follow-up care-update 2025].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2025Guideline
- Procalcitonin-guided antibiotic therapy may shorten length of treatment and may improve survival-a systematic review and meta-analysis.Critical care (London, England) · 2023Pooled it
- Cost-effectiveness of procalcitonin-guided antibiotic duration for hospitalized patients with sepsis.Critical care (London, England) · 2025Article
- The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2024.Journal of intensive care · 2025Article
- Prognostic Value of Procalcitonin and Procalcitonin Clearance in Septic Shock Patients: A Study from a Tertiary Teaching Hospital in Southern China.Infection and drug resistance · 2025Article
- Predictive value of peripheral blood indicators plus procalcitonin clearance rate for mortality in cancer patients with sepsis.American journal of cancer research · 2024Article
- Sepsis Management in Southeast Asia: A Review and Clinical Experience.Journal of clinical medicine · 2022Review
- Development and validation of a nomogram to predict the mortality risk in elderly patients with ARF.PeerJ · 2021Article
- Prognostic significance of PCT and CRP evaluation for adult ICU patients with sepsis and septic shock: retrospective analysis of 59 cases.The Journal of international medical research · 2019Article
- Nested case-control study of multiple serological indexes and Brighton pediatric early warming score in predicting death of children with sepsis.World journal of clinical cases · 2019Article
- [Diagnostic value of endogenous morphine in childhood sepsis].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2018Article
- The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2024.Acute medicine & surgeryArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThis study aimed to investigate the guiding effect of serum procalcitonin (PCT) on the antibiotic application to patients with sepsis.
methodsNinety-eight patients with sepsis treated in Renmin Hospital of Wuhan University, China from 2015-2017 were enrolled. They were divided into two equal groups of control group and the observation group. Patients in the observation group received the antibiotic therapy guided by PCT while patients in the control group received the regular antibiotic therapy. The conventional indexes, prognosis and clinical effects of the two groups were compared.
resultsThere were no statistical significance in the differences of the Acute Physiology and Chronic Health Evaluation II (APACHE-II) scores C-reactive protein (CRP) and white blood cell count (WBC) levels between the two groups. The duration of the antibiotic application to patients in the observation group was (7.74±0.61) d which was (10.22±0.78) d shorter than that to patients in the control group. The difference was statistically significant (
conclusionGuiding effects of the serum PCT on the application of antibiotics to patients with sepsis shorten the usage time of the antibiotics, ICU stay time and hospital stays.
Indexed as
Identifiers
29167772PMC5696693W2768013525What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.