ArticleF1000Research2017
Measuring evolutionary rates of proteins in a structural context.
Article in F1000Research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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Who cites it
11 citing papers in PubMed.
- Predictors of Protein Evolution in the drosophilid Immune System.Genome biology and evolution · 2026Article
- A quantitative comparison of the deleteriousness of missense and nonsense mutations using the structurally resolved human protein interactome.Protein science : a publication of the Protein Society · 2025Article
- Improved prediction of site-rates from structure with averaging across homologs.Protein science : a publication of the Protein Society · 2024Article
- Dissecting protein domain variability in the core RNA interference machinery of five insect orders.RNA biology · 2021Article
- SARS-CoV-2 mutations in Brazil: from genomics to putative clinical conditions.Scientific reports · 2021Article
- Unraveling the molecular basis of host cell receptor usage in SARS-CoV-2 and other human pathogenic β-CoVs.Computational and structural biotechnology journal · 2021Article
- Comparative study of the SBP-box gene family in rice siblings.Journal of biosciences · 2020Article
- Comparative structural and evolutionary analyses predict functional sites in the artemisinin resistance malaria protein K13.Scientific reports · 2019Article
- Phylogenomic analyses and distribution of terpene synthases amongBeilstein journal of organic chemistry · 2019Article
- Relative Evolutionary Rates in Proteins Are Largely Insensitive to the Substitution Model.Molecular biology and evolution · 2018Article
- Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
We describe how to measure site-specific rates of evolution in protein-coding genes and how to correlate these rates with structural features of the expressed protein, such as relative solvent accessibility, secondary structure, or weighted contact number. We present two alternative approaches to rate calculations: One based on relative amino-acid rates, and the other based on site-specific codon rates measured as
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.