ArticleFrontiers in psychiatry2017
Paired Associative Stimulation of the Temporal Cortex: Effects on the Auditory Steady-State Response.
Article in Frontiers in psychiatry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 8 citations in OpenAlex.
- Attention Networks in the Parietooccipital Cortex Modulate Activity of the Human Vestibular Cortex during Attentive Visual Processing.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020Article
- Auditory Neural Plasticity in Tinnitus Mechanisms and Management.Neural plasticity · 2020Review
- Neuromodulation of Gamma-Range Auditory Steady-State Responses: A Scoping Review of Brain Stimulation Studies.Frontiers in systems neuroscience · 2020Article
- Effects of cTBS on the Frequency-Following Response and Other Auditory Evoked Potentials.Frontiers in human neuroscience · 2020Article
- Effects of Acoustic Paired Associative Stimulation on Late Auditory Evoked Potentials.Brain topography · 2019Article
- Enhanced Auditory Steady-State Response Using an Optimized Chirp Stimulus-Evoked Paradigm.Sensors (Basel, Switzerland) · 2019Article
- Cortical markers of PAS-induced long-term potentiation and depression in the motor system: A TMS-EEG Registered Report.Imaging neuroscience (Cambridge, Mass.)Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPaired associative stimulation (PAS) is the repeated combination of a sensory stimulus with transcranial magnetic stimulation (TMS) in close temporal association. Recently, a study demonstrated that PAS of an auditory stimulus together with TMS of the temporal cortex is capable of changing the amplitude of auditory evoked potentials (AEP).
objectiveThis study examined the influence of tone duration and habituation in temporal cortex PAS as elicited by 40 and 20 Hz amplitude modulated auditory steady-state responses (aSSR).
methodsEighteen subjects participated in two experiments, including two PAS protocols each, which consisted of 200 auditory stimuli (4 kHz) paired with temporal cortex TMS with an interstimulus interval (ISI) of 45 ms between tone onset and TMS pulse, delivered at 0.1 Hz. Experiment 1 compared auditory stimuli with different lengths [PAS (23 ms) vs. PAS (400 ms)]. Experiment 2 investigated verum vs. sham PAS. aSSR for the paired tone (4 kHz) and a control tone (1 kHz) were measured pre- and post-interventional-using 40 Hz aSSR in experiment 1 and both 20 and 40 Hz aSSR in experiment 2.
resultsA statistically significant, sham-controlled decrease in amplitude was observed for the 20 Hz aSSR using the 4 kHz PAS carrier frequency in experiment 2.
conclusionFrequency-specific effects for the 20 Hz aSSR confirm the feasibility of auditory PAS and highlight the secondary auditory cortex as its target site, introducing new possible treatment protocols for patients suffering from tinnitus. The amplitude decrease can be explained by principles of spike timing-dependent plasticity and the superposition model of aSSR.
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