Evidence map›Paper›PMID 29167560›Full record

ArticleScientific reports2017

Transcriptome responses of Streptococcus mutans to peroxide stress: identification of novel antioxidant pathways regulated by Spx.

Jessica K Kajfasz, Tridib Ganguly, Emily L Hardin, Jacqueline Abranches, José A Lemos

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 44 citations in OpenAlex.

  1. Article
  2. SppR inFrontiers in cellular and infection microbiology · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. SMU_1361c regulates the oxidative stress response ofApplied and environmental microbiology · 2024
    Article
  9. Multiple factors regulate the expression ofFrontiers in cellular and infection microbiology · 2024
    Article
  10. Review
  11. Article
  12. Catalase produced bymSphere · 2023
    Article
  13. Article
  14. Article
  15. Article
  16. Disruption of theJournal of bacteriology · 2022
    Article
  17. Transcriptomic Stress Response inMicroorganisms · 2022
    Article
  18. Article
  19. Article
  20. Frontiers in microbiology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Jessica K KajfaszDepartment of Oral Biology, University of Florida College of Dentistry, Gainesville, FL, 32608, USA.
Tridib GangulyDepartment of Oral Biology, University of Florida College of Dentistry, Gainesville, FL, 32608, USA.
Emily L HardinDepartment of Oral Biology, University of Florida College of Dentistry, Gainesville, FL, 32608, USA.
Jacqueline AbranchesDepartment of Oral Biology, University of Florida College of Dentistry, Gainesville, FL, 32608, USA.
José A LemosDepartment of Oral Biology, University of Florida College of Dentistry, Gainesville, FL, 32608, USA. jlemos@dental.ufl.edu.
Florida College · USUniversity of Florida · US

Funding

Role of the Spx Regulator in Streptococcus mutansR01DE019783 · NIDCR · UNIVERSITY OF ROCHESTER · PI LEMOS, JOSE A · 2010 to 2020
$3.7M
NIDCR NIH HHS R01 DE019783
6 · The paper itself

Abstract

The oxidative stress regulator Spx is ubiquitously found among Gram-positive bacteria. Previously, we reported identification of two Spx proteins in Streptococcus mutans - SpxA1 was the primary activator of oxidative stress genes whereas SpxA2 served a backup role. Here, we used RNA sequencing to uncover the scope of the H

Indexed as

AntioxidantsBacterial ProteinsGene Expression Regulation, BacterialHydrogen PeroxideOxidative StressStreptococcus mutansAntioxidantsBacterial ProteinsHydrogen Peroxide

Identifiers

PMID29167560
PMCPMC5700188
OpenAlexW2770079165

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.