Evidence map›Paper›PMID 29167492›Full record

ArticleScientific reports2017

Radioligand binding analysis of α

Jenny-Ann Phan, Anne M Landau, Steen Jakobsen, Dean F Wong, Albert Gjedde

Erratum issuedOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.8field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Relative Strengths of Three Linearizations of Receptor Availability: Saturation, Inhibition, and Occupancy Plots.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2022
    Article
  3. Transient equilibrium determination of dopamine DFrontiers in nuclear medicine · 2022
    Article
  4. NRM 2021 Abstract Booklet.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2021
    Article
  5. Quantitative Rodent Brain Receptor Imaging.Molecular imaging and biology · 2020
    Review
  6. Impaired Glymphatic Transport in Spontaneously Hypertensive Rats.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2019
    Article
  7. Article
  8. Frontiers in aging neuroscience · 2018
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 4 countries.

Jenny-Ann PhanDepartment of Biomedicine, Aarhus University, Aarhus, 8000, Denmark.
Anne M LandauDepartment of Nuclear Medicine and PET centre, Aarhus University Hospital, Aarhus, 8000, Denmark.
Steen JakobsenDepartment of Nuclear Medicine and PET centre, Aarhus University Hospital, Aarhus, 8000, Denmark.
Dean F WongRadiology, Psychiatry, Neuroscience, Neurology, Environmental Health Sciences, Johns Hopkins University, Johns Hopkins Medical Institutions, JHOC Bldg room 3245, 601 N. Caroline St., Baltimore, MD, 21287, USA.
Albert GjeddeDepartment of Neuroscience, University of Copenhagen, Copenhagen, 2200, Denmark. gjedde@sund.ku.dk.ORCID 0000-0002-3756-7401
Aarhus University Hospital · DKAarhus University · DKJohns Hopkins University · USUniversity of Copenhagen · DK

Funding

PET Imaging of alpha 7 and alpha4beta2-nAChR in Schizophrenia: Cognitive RelationshipsR01MH107197 · NIMH · WASHINGTON UNIVERSITY · PI HORTI, ANDREW G, WONG, DEAN FOSTER · 2015 to 2025
$4.6M
NIMH NIH HHS R01 MH107197
6 · The paper itself

Abstract

We describe a novel method of kinetic analysis of radioligand binding to neuroreceptors in brain in vivo, here applied to noradrenaline receptors in rat brain. The method uses positron emission tomography (PET) of [

Indexed as

AnimalsBlood ProteinsBrainFemaleProtein BindingRatsRats, Sprague-DawleyReceptors, Adrenergic, alpha-2YohimbineBlood ProteinsReceptors, Adrenergic, alpha-2Yohimbine

Identifiers

PMID29167492
PMCPMC5700124
OpenAlexW2769065815

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.