Evidence map›Paper›PMID 29167454›Full record

ArticleBlood cancer journal2017

NR4A1 inhibition synergizes with ibrutinib in killing mantle cell lymphoma cells.

Yangguang Li, Fangyu Wang, Li Lu, Fen Zhu, Shengjian Huang, Krystle Nomie, Liang Zhang, David T Yang, Wei Huang, Brad S Kahl and 3 more

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Blood cancer journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Yangguang LiDepartment of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI, 53792, USA.
Fangyu WangDepartment of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI, 53792, USA.
Li LuDepartment of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI, 53792, USA.
Fen ZhuDepartment of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI, 53792, USA.
Shengjian HuangDepartment of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
Krystle NomieDepartment of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
Liang ZhangDepartment of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
David T YangCarbone Cancer Center, University of Wisconsin School of Medicine and Public Health, Madison, WI, 53792, USA.
Wei HuangDepartment of Pathology and Laboratory Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI, 53792, USA.
Brad S KahlDepartment of Medicine, Washington University School of Medicine, St. Louis, MO, 63110, USA.
Stephen SafeDepartment of Veterinary Physiology and Pharmacology, Texas A&M University, College Station, TX, 77843, USA.
Michael WangDepartment of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
Lixin RuiDepartment of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI, 53792, USA. lrui@medicine.wisc.edu.

Funding

Institutional Clinical and Translational Science AwardUL1TR000427 · NCATS · UNIVERSITY OF WISCONSIN-MADISON · PI DREZNER, MARC KENNETH · 2012 to 2016
$32.2M
Epigenetic Gene Regulation by JAK1 Kinase in Diffuse Large B-Cell LymphomaR01CA187299 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI RUI, LIXIN · 2015 to 2019
$1.7M
NCATS NIH HHS UL1 TR000427NCI NIH HHS R01 CA187299
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdenineAntineoplastic Combined Chemotherapy ProtocolsApoptosisCell Line, TumorDrug SynergismHumansLymphoma, Mantle-CellNuclear Receptor Subfamily 4, Group A, Member 1OncogenesPiperidinesPyrazolesPyrimidinesAdenineibrutinibNR4A1 protein, humanNuclear Receptor Subfamily 4, Group A, Member 1PiperidinesPyrazolesPyrimidines

Identifiers

PMID29167454
PMCPMC5802686

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.