ArticleNature communications2017
Widespread theta synchrony and high-frequency desynchronization underlies enhanced cognition.
Article in Nature communications, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 118 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
118 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Effects of transcranial alternating current stimulation on cognitive function in older adults: a systematic review and meta-analysis of randomized controlled trials.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025Pooled it
- A Systematic Review of tACS Effects on Cognitive Functioning in Older Adults Across the Healthy to Dementia Spectrum.Neuropsychology review · 2024Pooled it
- Systematic Review and Meta-Analysis on the Effects of Neurofeedback Training of Theta Activity on Working Memory and Episodic Memory in Healthy Population.International journal of environmental research and public health · 2022Pooled it
- Theta tACS impairs episodic memory more than tDCS.Scientific reports · 2023Trial
- Hippocampal CA1 gamma power predicts the precision of spatial memory judgments.Proceedings of the National Academy of Sciences of the United States of America · 2018Trial
- Whole-brain millisecond-scale effective connectivity of auditory and visual naming.NeuroImage · 2026Article
- Article
- Concept Cells and the Neural Bases of Human Memory.Acta physiologica (Oxford, England) · 2026Review
- Quantum-inspired entanglement between collaborating brains during human memory encoding.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Medial Pulvinar Nucleus as a Causal Hub for Heteromodal Naming.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Network hubs supporting memory encoding: Implications for cognitive preservation in epilepsy surgery.Epilepsia · 2026Article
- Processing of different word list lengths during encoding and retrieval in Broca's area.Frontiers in human neuroscience · 2026Article
- Episodic memory involves transient and sparse connectivity aligned to both internal and external events.PLoS biology · 2025Article
- Frontal Theta Modulation in Sequential Working Memory: the Impact of Spatial Regularity and Scenario.Brain topography · 2025Article
- Preoperative network activity predicts the response to subthalamic DBS for Parkinson's disease.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025Article
- Phase Consistency Dynamics of Memory Encoding.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Article
- Theta-phase locking of single neurons during human spatial memory.Nature communications · 2025Article
- Investigating neural correlates of attention in relation to the development of executive functions in early childhood.Scientific reports · 2025Article
- Neural Dynamics of Visual Stream Interactions During Memory-Guided Actions Investigated by Intracranial EEG.Neuroscience bulletin · 2025Article
58 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors.
Funding
Abstract
The idea that synchronous neural activity underlies cognition has driven an extensive body of research in human and animal neuroscience. Yet, insufficient data on intracranial electrical connectivity has precluded a direct test of this hypothesis in a whole-brain setting. Through the lens of memory encoding and retrieval processes, we construct whole-brain connectivity maps of fast gamma (30-100 Hz) and slow theta (3-8 Hz) spectral neural activity, based on data from 294 neurosurgical patients fitted with indwelling electrodes. Here we report that gamma networks desynchronize and theta networks synchronize during encoding and retrieval. Furthermore, for nearly all brain regions we studied, gamma power rises as that region desynchronizes with gamma activity elsewhere in the brain, establishing gamma as a largely asynchronous phenomenon. The abundant phenomenon of theta synchrony is positively correlated with a brain region's gamma power, suggesting a predominant low-frequency mechanism for inter-regional communication.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.