Evidence map›Paper›PMID 29167408›Full record

ArticleJournal of lipid research2018

Conjugated linoleic acid prevents age-dependent neurodegeneration in a mouse model of neuropsychiatric lupus via the activation of an adaptive response.

Antonio Monaco, Ida Ferrandino, Floriana Boscaino, Ennio Cocca, Luisa Cigliano, Francesco Maurano, Diomira Luongo, Maria Stefania Spagnuolo, Mauro Rossi, Paolo Bergamo

Open access · hybridAbstract read
In one paragraph

Article in Journal of lipid research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 42 citations in OpenAlex.

  1. Article
  2. Conjugated Linoleic Acid in Cancer Therapy.Current drug delivery · 2025
    Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. Review
  16. From Systemic Inflammation to Neuroinflammation: The Case of Neurolupus.International journal of molecular sciences · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Antonio MonacoDepartment of Biology, University "Federico II" of Naples, Italy.
Ida FerrandinoDepartment of Biology, University "Federico II" of Naples, Italy.
Floriana BoscainoInstitute of Food Sciences, National Research Council (CNR-ISA), Avellino, Italy.
Ennio CoccaInstitute of Biosciences and Bio-Resources, National Research Council (CNR-IBBR), Naples, Italy.
Luisa CiglianoDepartment of Biology, University "Federico II" of Naples, Italy.
Francesco MauranoInstitute of Food Sciences, National Research Council (CNR-ISA), Avellino, Italy.
Diomira LuongoInstitute of Food Sciences, National Research Council (CNR-ISA), Avellino, Italy.
Maria Stefania SpagnuoloInstitute for Animal Production System in Mediterranean Environment, National Research Council (ISPAAM, CNR) Naples, Italy.
Mauro RossiInstitute of Food Sciences, National Research Council (CNR-ISA), Avellino, Italy.
Paolo BergamoInstitute of Food Sciences, National Research Council (CNR-ISA), Avellino, Italy p.bergamo@isa.cnr.it.
National Research Council · ITFederico II University Hospital · ITInstitute of Food Science · ITIstituto per il Sistema Produzione Animale in Ambiente Mediterraneo · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oxidative stress is a key mediator of autoimmune/neurodegenerative disorders. The antioxidant/anti-inflammatory effect of a synthetic conjugated linoleic acid (CLA) mixture in MRL/MpJ-Fas

Indexed as

Disease Models, AnimalAdministration, OralAge FactorsAnimalsFemaleLinoleic Acids, ConjugatedLupus Erythematosus, SystemicMaleMiceMice, Inbred BALB CNerve DegenerationOxidative StressLinoleic Acids, ConjugatedastrogliosisautophagyneuroprotectionNrf2 pathway

Identifiers

PMID29167408
PMCPMC5748496
OpenAlexW2768712880

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.