Evidence map›Paper›PMID 29167402›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2018

The Role of Cysteine String Protein α Phosphorylation at Serine 10 and 34 by Protein Kinase Cγ for Presynaptic Maintenance.

Toshihiko Shirafuji, Takehiko Ueyama, Naoko Adachi, Ken-Ichi Yoshino, Yusuke Sotomaru, Junsuke Uwada, Azumi Kaneoka, Taro Ueda, Shigeru Tanaka, Izumi Hide and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Toshihiko ShirafujiDepartment of Molecular and Pharmacological Neuroscience, Graduate School of Biomedical Sciences, and sirafuji@hiroshima-u.ac.jp.
Takehiko UeyamaLaboratory of Molecular Pharmacology, Biosignal Research Center, Kobe University, Kobe 657-8501, Japan, and.ORCID 0000-0002-5647-3937
Naoko AdachiLaboratory of Molecular Pharmacology, Biosignal Research Center, Kobe University, Kobe 657-8501, Japan, and.ORCID 0000-0002-8797-0717
Ken-Ichi YoshinoLaboratory of Molecular Pharmacology, Biosignal Research Center, Kobe University, Kobe 657-8501, Japan, and.
Yusuke SotomaruNatural Science Center for Basic Research and Development, Hiroshima University, Hiroshima 734-8551, Japan.
Junsuke UwadaDivision of Cellular Signal Transduction, Department of Biochemistry, Asahikawa Medical University, Asahikawa 078-8510, Japan.
Azumi KaneokaDepartment of Molecular and Pharmacological Neuroscience, Graduate School of Biomedical Sciences, and.
Taro UedaDepartment of Molecular and Pharmacological Neuroscience, Graduate School of Biomedical Sciences, and.
Shigeru TanakaDepartment of Molecular and Pharmacological Neuroscience, Graduate School of Biomedical Sciences, and.
Izumi HideDepartment of Molecular and Pharmacological Neuroscience, Graduate School of Biomedical Sciences, and.
Naoaki SaitoLaboratory of Molecular Pharmacology, Biosignal Research Center, Kobe University, Kobe 657-8501, Japan, and.ORCID 0000-0003-3389-1367
Norio SakaiDepartment of Molecular and Pharmacological Neuroscience, Graduate School of Biomedical Sciences, and.
Hologic (Germany) · DEKobe University · JPHiroshima University · JPAsahikawa Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Protein kinase Cγ (PKCγ) knock-out (KO) animals exhibit symptoms of Parkinson's disease (PD), including dopaminergic neuronal loss in the substantia nigra. However, the PKCγ substrates responsible for the survival of dopaminergic neurons

Indexed as

AnimalsChlorocebus aethiopsCOS CellsDopaminergic NeuronsHSP40 Heat-Shock ProteinsHumansMaleMembrane ProteinsMiceMice, KnockoutNerve DegenerationParkinson DiseasePC12 CellsPhosphorylationPresynaptic TerminalsProtein Kinase Ccysteine string proteinHSP40 Heat-Shock ProteinsMembrane ProteinsProtein Kinase Cprotein kinase C gammaSerinechaperonecysteine string protein αphosphorylationpresynapseprotein kinase C

Identifiers

PMID29167402
PMCPMC6596106
OpenAlexW2768445509

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.