Evidence map›Paper›PMID 29167374›Full record

SynthesisProceedings of the National Academy of Sciences of the United States of America2017

FMRFamide-like peptides expand the behavioral repertoire of a densely connected nervous system.

James Siho Lee, Pei-Yin Shih, Oren N Schaedel, Porfirio Quintero-Cadena, Alicia K Rogers, Paul W Sternberg

Open access · bronzeAbstract readMeta-Analysis
In one paragraph

Synthesis in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 90 citations in OpenAlex.

  1. Article
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  3. Article
  4. Review
  5. Review
  6. A gene expression atlas of a juvenile nervous system.bioRxiv : the preprint server for biology · 2025
    Article
  7. Article
  8. Article
  9. GPCR Sense Communication Among Interaction Nematodes with Other Organisms.International journal of molecular sciences · 2025
    Review
  10. The many roads toJournal of biosciences · 2025
    Review
  11. Article
  12. Article
  13. Sensory integration of food and population density during the diapause exit decision involves insulin-like signaling inProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  14. Review
  15. Glial expression of a steroidogenic enzyme underlies natural variation in hitchhiking behavior.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

James Siho LeeDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125.ORCID 0000-0002-4959-7237
Pei-Yin ShihDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125.ORCID 0000-0003-3082-9242
Oren N SchaedelDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125.
Porfirio Quintero-CadenaDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125.ORCID 0000-0003-0067-5844
Alicia K RogersDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125.
Paul W SternbergDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125; pws@caltech.edu.ORCID 0000-0002-4959-7237
California Institute of Technology · US

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Aric L Daul, Ann E. Rougvie · 2012 to 2026
$7.5M
Howard Hughes Medical InstituteNIH HHS P40 OD010440
6 · The paper itself

Abstract

Animals, including humans, can adapt to environmental stress through phenotypic plasticity. The free-living nematode

Indexed as

AnimalsCaenorhabditis elegansCarbon DioxideClustered Regularly Interspaced Short Palindromic RepeatsFMRFamideGene Knockdown TechniquesGenes, HelminthLarvaNeuropeptidesPhenotypeReproductionRNA, HelminthSequence Analysis, RNASignal TransductionStress, PhysiologicalCarbon DioxideFMRFamideNeuropeptidesRNA, HelminthdauerFMRFamideneuropeptidephenotypic plasticityRNA-seq

Identifiers

PMID29167374
PMCPMC5740649
OpenAlexW2769168599

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.