Evidence map›Paper›PMID 29167298›Full record

ArticleThe European respiratory journal2017

Prevalence and burden of chronic bronchitis symptoms: results from the BOLD study.

Filip Mejza, Louisa Gnatiuc, A Sonia Buist, William M Vollmer, Bernd Lamprecht, Daniel O Obaseki, Pawel Nastalek, Ewa Nizankowska-Mogilnicka, Peter G J Burney, BOLD collaborators and 1 more

Registry-linked trialOpen access · bronzeAbstract readMulticenter Study
In one paragraph

Article in The European respiratory journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06134947 (Assessment of Right Ventricular Function Among Children With Chronic Lung Disease), which is not on this map. Cited by 60 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
60citing papers in PubMed, 4 pooled it
5.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06134947 unknown statusnot on this mapstarted 2023, after this paper: background citation

Assessment of Right Ventricular Function Among Children With Chronic Lung Disease

TypeobservationalSponsorAssiut UniversityRan2023 to 2025Enrolled75ConditionsRight Ventricular FunctionArmsEchocardiographic examination
3 · Its place in the literature

Who cites it

60 citing papers in PubMed, 4 syntheses or guidelines pooled it, 101 citations in OpenAlex.

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  12. Impact of bronchitis variability on outcomes of COPD.BMJ open respiratory research · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 5 countries.

Filip MejzaII Dept of Internal Medicine, Jagiellonian University Medical College, Krakow, Poland filipmejza@hotmail.com.
Louisa GnatiucDept of Respiratory Epidemiology, Occupational Medicine and Public Health, Imperial College London, London, UK.
A Sonia BuistPulmonary and Critical Care Medicine, Oregon Health and Science University, Portland, OR, USA.
William M VollmerCenter for Health Research, Kaiser Permanente, Portland, OR, USA.
Bernd LamprechtDept of Pulmonary Medicine, Kepler University Hospital, Linz, Austria.
Daniel O ObasekiDept of Medicine, Obafemi Awolowo University, Ile-Ife, Nigeria.
Pawel NastalekII Dept of Internal Medicine, Jagiellonian University Medical College, Krakow, Poland.
Ewa Nizankowska-MogilnickaII Dept of Internal Medicine, Jagiellonian University Medical College, Krakow, Poland.
Peter G J BurneyDept of Respiratory Epidemiology, Occupational Medicine and Public Health, Imperial College London, London, UK.
BOLD collaborators
BOLD study collaborators
Jagiellonian University · PLImperial College London · GBKaiser Permanente Center for Health Research · USKepler Universitätsklinikum · ATObafemi Awolowo University · NGOregon Health & Science University · US

Funding

Wellcome Trust
6 · The paper itself

Abstract

We studied the prevalence, burden and potential risk factors for chronic bronchitis symptoms in the Burden of Obstructive Lung Disease study.Representative population-based samples of adults aged ≥40 years were selected in participating sites. Participants completed questionnaires and spirometry. Chronic bronchitis symptoms were defined as chronic cough and phlegm on most days for ≥3 months each year for ≥2 years.Data from 24 855 subjects from 33 sites in 29 countries were analysed. There were significant differences in the prevalence of self-reported symptoms meeting our definition of chronic bronchitis across sites, from 10.8% in Lexington (KY, USA), to 0% in Ile-Ife (Nigeria) and Blantyre (Malawi). Older age, less education, current smoking, occupational exposure to fumes, self-reported diagnosis of asthma or lung cancer and family history of chronic lung disease were all associated with increased risk of chronic bronchitis. Chronic bronchitis symptoms were associated with worse lung function, more dyspnoea, increased risk of respiratory exacerbations and reduced quality of life, independent of the presence of other lung diseases.The prevalence of chronic bronchitis symptoms varied widely across the studied sites. Chronic bronchitis symptoms were associated with significant burden both in individuals with chronic airflow obstruction and those with normal lung function.

Indexed as

Quality of LifeAdultAgedAge DistributionBronchitis, ChronicCost of IllnessCoughDyspneaFemaleForced Expiratory VolumeHumansInternationalityLogistic ModelsLungMaleMiddle Aged

Identifiers

PMID29167298
PMCPMC5699921
OpenAlexW2769789030

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.