Evidence map›Paper›PMID 29167115›Full record

ArticleAmerican journal of physiology. Gastrointestinal and liver physiology2018

Epigenetic modulation of intestinal Na

Anoop Kumar, Pooja Malhotra, Hayley Coffing, Shubha Priyamvada, Arivarasu N Anbazhagan, Harish R Krishnan, Ravinder K Gill, Waddah A Alrefai, David P Gavin, Subhash C Pandey and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in American journal of physiology. Gastrointestinal and liver physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.2field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Anoop KumarDivision of Gastroenterology and Hepatology, Department of Medicine, University of Illinois at Chicago , Chicago, Illinois.
Pooja MalhotraDivision of Gastroenterology and Hepatology, Department of Medicine, University of Illinois at Chicago , Chicago, Illinois.
Hayley CoffingDivision of Gastroenterology and Hepatology, Department of Medicine, University of Illinois at Chicago , Chicago, Illinois.
Shubha PriyamvadaDivision of Gastroenterology and Hepatology, Department of Medicine, University of Illinois at Chicago , Chicago, Illinois.
Arivarasu N AnbazhaganDivision of Gastroenterology and Hepatology, Department of Medicine, University of Illinois at Chicago , Chicago, Illinois.
Harish R KrishnanCenter for Alcohol Research in Epigenetics, Department of Psychiatry, University of Illinois at Chicago , Chicago, Illinois.
Ravinder K GillDivision of Gastroenterology and Hepatology, Department of Medicine, University of Illinois at Chicago , Chicago, Illinois.
Waddah A AlrefaiDivision of Gastroenterology and Hepatology, Department of Medicine, University of Illinois at Chicago , Chicago, Illinois.
David P GavinCenter for Alcohol Research in Epigenetics, Department of Psychiatry, University of Illinois at Chicago , Chicago, Illinois.
Subhash C PandeyCenter for Alcohol Research in Epigenetics, Department of Psychiatry, University of Illinois at Chicago , Chicago, Illinois.
Pradeep K DudejaDivision of Gastroenterology and Hepatology, Department of Medicine, University of Illinois at Chicago , Chicago, Illinois.
Seema SaksenaDivision of Gastroenterology and Hepatology, Department of Medicine, University of Illinois at Chicago , Chicago, Illinois.
University of Illinois Chicago · USJesse Brown VA Medical Center · US

Funding

Pilot Project Program P50AA022538 · NIAAA · UNIVERSITY OF ILLINOIS AT CHICAGO · PI SUBHASH C. PANDEY · 2015 to 2026
$21.3M
Transporter Trafficking Mechanisms in Infectious DiarrheaR01DK092441 · NIDDK · UNIVERSITY OF ILLINOIS AT CHICAGO · PI DUDEJA, PRADEEP K · 2011 to 2020
$3.0M
Intestinal 5-HT Transporter: A novel therapeutic target for GI disordersR01DK098170 · NIDDK · UNIVERSITY OF ILLINOIS AT CHICAGO · PI GILL, RAVINDER K · 2014 to 2022
$3.0M
Probiotics:Potential Therapeutic Roles in DiarrheaR01DK081858 · NIDDK · UNIVERSITY OF ILLINOIS AT CHICAGO · PI DUDEJA, PRADEEP K · 2008 to 2017
$2.5M
Neuronal PARP activity in fetal alcohol spectrum disordersR01AA025035 · NIAAA · UNIVERSITY OF ILLINOIS AT CHICAGO · PI PANDEY, SUBHASH C. · 2017 to 2021
$1.8M
Mechanisms of Regulation of Intestinal Cl Absorption in IBD Associated DiarrheaI01BX002011 · VA · JESSE BROWN VA MEDICAL CENTER · PI DUDEJA, PRADEEP K · 2013 to 2024
–
Regulation of Intestinal Sodium Absorption in Health and DiseaseI01BX002867 · VA · JESSE BROWN VA MEDICAL CENTER · PI Seema Saksena · 2016 to 2026
–
BLRD VA I01 BX002011BLRD VA I01 BX002867BLRD VA IK2 BX001650NIAAA NIH HHS P50 AA022538NIAAA NIH HHS R01 AA025035NIDDK NIH HHS R01 DK081858NIDDK NIH HHS R01 DK092441NIDDK NIH HHS R01 DK098170
6 · The paper itself

Abstract

Na

Indexed as

DNA MethylationEpigenesis, GeneticAnimalsAntigens, DifferentiationAzacitidineCaco-2 CellsColonDNA Modification MethylasesEnzyme InhibitorsGADD45 ProteinsGene Expression RegulationHumansIleumMaleMice, Inbred C57BLMice, KnockoutAntigens, DifferentiationAzacitidineDNA Modification MethylasesEnzyme InhibitorsGADD45B protein, humanGadd45b protein, mouseGADD45 ProteinsSLC9A3 protein, humanSodium-Hydrogen Exchanger 35-azacytidinedeoxyribonucleic acid demethylationdeoxyribonucleic acid methyltransferasegrowth arrest and deoxyribonucleic acid damage-inducible 45bSLC9A3

Identifiers

PMID29167115
PMCPMC5899241
OpenAlexW2768637428

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.