Evidence map›Paper›PMID 29166976›Full record

ArticleEpidemiology and infection2017

Clinical, laboratory and epidemiological aspects of HPV infection in a low-income population from South Bahia, Brazil.

S R Gadelha, D M V Soares-Barreto, G B Costa, V C N Leal, L G S Gomes, U R Santos, G C S Ferreira, L D Carvalho, S M V Soraes-Almeida, M A G Mello and 4 more

Open access · bronzeAbstract read
In one paragraph

Article in Epidemiology and infection, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 1 country.

S R GadelhaLaboratório de Farmacogenômica e Epidemiologia Molecular,Departamento de Ciências Biológicas,Universidade Estadual de Santa Cruz,Ilhéus,Bahia,Brazil.
D M V Soares-BarretoLaboratório de Farmacogenômica e Epidemiologia Molecular,Departamento de Ciências Biológicas,Universidade Estadual de Santa Cruz,Ilhéus,Bahia,Brazil.
G B CostaLaboratório de Farmacogenômica e Epidemiologia Molecular,Departamento de Ciências Biológicas,Universidade Estadual de Santa Cruz,Ilhéus,Bahia,Brazil.
V C N LealLaboratório de Imunogenética,Departamento de Imunologia,Instituto de Ciências Biomédicas,Universidade de São Paulo,São Paulo,SP,Brazil.
L G S GomesLaboratório de Farmacogenômica e Epidemiologia Molecular,Departamento de Ciências Biológicas,Universidade Estadual de Santa Cruz,Ilhéus,Bahia,Brazil.
U R SantosLaboratório de Farmacogenômica e Epidemiologia Molecular,Departamento de Ciências Biológicas,Universidade Estadual de Santa Cruz,Ilhéus,Bahia,Brazil.
G C S FerreiraLaboratório de Farmacogenômica e Epidemiologia Molecular,Departamento de Ciências Biológicas,Universidade Estadual de Santa Cruz,Ilhéus,Bahia,Brazil.
L D CarvalhoLaboratório de Farmacogenômica e Epidemiologia Molecular,Departamento de Ciências Biológicas,Universidade Estadual de Santa Cruz,Ilhéus,Bahia,Brazil.
S M V Soraes-AlmeidaLaboratório de Farmacogenômica e Epidemiologia Molecular,Departamento de Ciências Biológicas,Universidade Estadual de Santa Cruz,Ilhéus,Bahia,Brazil.
M A G MelloFaculdade de Ilhéus,Bahia,Brazil.
A P M MarianoLaboratório de Farmacogenômica e Epidemiologia Molecular,Departamento de Ciências Biológicas,Universidade Estadual de Santa Cruz,Ilhéus,Bahia,Brazil.
S M B SousaDepartamento de Ciências Naturais,Genética Humana e de Populações,Universidade Estadual do Sudoeste da Bahia,Vitória da Conquista,Bahia,Brazil.
A R VagoDepartamento de Morfologia,Instituto de Ciências Biológicas,Universidade Federal de Minas Gerais,Belo Horizonte,Minas Gerais,Brazil.
L J MarinLaboratório de Farmacogenômica e Epidemiologia Molecular,Departamento de Ciências Biológicas,Universidade Estadual de Santa Cruz,Ilhéus,Bahia,Brazil.
Universidade Estadual de Santa Cruz · BRUniversidade Federal de Minas Gerais · BRSouthwest Bahia State University · BRUniversidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to determine the prevalence and risk factors for human papillomavirus (HPV) infection in the Southern region of the State of Bahia, evaluating the performance of alternative complementary methods for cervical lesion detection. Cervical samples from women who attended healthcare units were collected and diagnosed by visual inspection, cervical cytology and nested polymerase chain reaction (PCR). Moreover, hemi-nested PCR was performed to detect different HPV genotypes. The prevalence of HPV infection was 47·7%, with genotype 16 detected in most cases. Infection was associated with dyspareunia and bleeding (P < 0·001, odds ratio (OR) 5·6, 95% confidence interval (CI) 2·815-11·14) and hormonal contraceptive use (P = 0·007, OR 2·33, 95% CI 1·25-4·34). There was a positive correlation between positive PCR and positive visual inspection, cervical cytology and symptoms reported. Furthermore, visual inspection was twice as specific, and had a greater positive predictive value than cytology. We showed a high prevalence of HPV infection in Southern Bahia, with HPV 16 being the most common type, and visual inspection being most effective at detecting HPV lesions, corroborating the suggestion that it can be applied in routine gynecologic examinations for low-income populations.

Indexed as

AdolescentAdultAgedAged, 80 and overBrazilCervix UteriCross-Sectional StudiesEarly Detection of CancerFemaleHumansMiddle AgedPapillomavirus InfectionsPolymerase Chain ReactionPovertyPrevalenceRisk FactorsCervical cancer screeninghigh risk HPV typesHPVlow-income populationpublic health burdenrisk factorsvisual inspection of the cervix with acetic acid

Identifiers

PMID29166976
PMCPMC9148761
OpenAlexW2770428449

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.