Evidence map›Paper›PMID 29166760›Full record

ArticleThe Korean journal of internal medicine2018

Clinical characteristics and treatment propensity in elderly patients aged over 80 years with colorectal cancer.

Yun Hwa Jung, Jae Young Kim, Yu Na Jang, Sang Hoon Yoo, Gyo Hui Kim, Kang Min Lee, In Kyu Lee, Su Mi Chung, In Sook Woo

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Article in The Korean journal of internal medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. JCO precision oncology · 2026
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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Yun Hwa JungDivision of Medical Oncology, Department of Internal Medicine, College of Medicine, Yeouido St. Mary's Hospital, The Catholic University of Korea, Seoul, Korea.
Jae Young KimDepartment of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Yu Na JangDepartment of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Sang Hoon YooDepartment of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Gyo Hui KimDepartment of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Kang Min LeeDepartment of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea.
In Kyu LeeDepartment of Surgery, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Su Mi ChungDepartment of Radiation Oncology, College of Medicine, The Catholic University of Korea, Seoul, Korea.
In Sook WooDivision of Medical Oncology, Department of Internal Medicine, College of Medicine, Yeouido St. Mary's Hospital, The Catholic University of Korea, Seoul, Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimsElderly patients (≥ 80 years) with colorectal cancer (CRC) tend to avoid active treatment at the time of diagnosis despite of recent advances in treatment. The aim of this study was to determine treatment propensity of elderly patients aged ≥ 80 years with CRC in clinical practice and the impact of anticancer treatment on overall survival (OS).

methodsMedical charts of 152 elderly patients (aged ≥ 80 years) diagnosed with CRC between 1998 and 2012 were retrospectively reviewed. Patients' clinical characteristics, treatment modalities received, and clinical outcome were analyzed.

resultsTheir median age was 82 years (range, 80 to 98). Of 152 patients, 148 were assessable for the extent of the disease. Eighty-two of 98 patients with localized disease and 28 of 50 patients with metastatic disease had received surgery or chemotherapy or both. Surgery was performed in 79 of 98 patients with localized disease and 15 of 50 patients with metastatic disease. Chemotherapy was administered in only 24 of 50 patients with metastatic disease. Patients who received anticancer treatment according to disease extent showed significantly longer OS compared to untreated patients (localized disease, 76.2 months vs. 15.4 months, p = 0.000; metastatic disease, 9.9 months vs. 2.6 months, p = 0.001). Along with anticancer treatment, favorable performance status (PS) was associated with longer OS in multivariate analysis of clinical outcome.

conclusionElderly patients aged ≥ 80 years with CRC tended to receive less treatment for metastatic disease. Nevertheless, anticancer treatment in patients with favorable PS was effective in prolonging OS regardless of disease extent.

Indexed as

ColectomyAged, 80 and overAge FactorsAntineoplastic Combined Chemotherapy ProtocolsChemotherapy, AdjuvantColorectal NeoplasmsFemaleHumansMaleNeoplasm MetastasisNeoplasm StagingPalliative CareRetrospective StudiesRisk FactorsTime FactorsTreatment OutcomeAgedColorectal neoplasmsColorectal surgeryDrug therapy

Identifiers

PMID29166760
PMCPMC6234404

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