Evidence map›Paper›PMID 29166759›Full record

ArticleThe Korean journal of internal medicine2019

Magnetic resonance imaging-assessed synovial and bone changes in hand and wrist joints of rheumatoid arthritis patients.

Kyung-Ann Lee, Sang-Ho Min, Tae-Hyung Kim, Sang-Heon Lee, Hae-Rim Kim

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Korean journal of internal medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06459453 (Effects of Kaltenborn Versus Mulligan Techniques on Pain, Range of Motion and Functional Disability in Patients With Rheumatoid Arthritis Of The Wrist.), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06459453 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Effects of Kaltenborn Versus Mulligan Techniques on Pain, Range of Motion and Functional Disability in Patients With Rheumatoid Arthritis Of The Wrist.

TypeinterventionalSponsorRiphah International UniversityRan2023 to 2024Enrolled34ConditionsRheumatoid ArthritisArmsKaltenborn, Mulligan
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Kyung-Ann LeeDivision of Rheumatology, Department of Internal Medicine, Konkuk University Medical Center, Seoul, Korea.
Sang-Ho MinDepartment of Internal Medicine, Konkuk University Medical Center, Seoul, Korea.
Tae-Hyung KimDepartment of Radiology, Konkuk University Medical Center, Seoul, Korea.
Sang-Heon LeeDivision of Rheumatology, Department of Internal Medicine, Konkuk University Medical Center, Seoul, Korea.
Hae-Rim KimDivision of Rheumatology, Department of Internal Medicine, Konkuk University Medical Center, Seoul, Korea.
Konkuk University Medical Center · KR

Funding

Ministry of Education, Science and Technology 2015R1D1A1A01056763National Research Foundation of Korea
6 · The paper itself

Abstract

BACKGROUND/

aimsMagnetic resonance imaging (MRI) is a sensitive and useful method for the detection of synovitis and joint destruction in rheumatoid arthritis (RA) patients. However, the patterns of MRI-detected bone erosion, bone marrow edema (BME), synovitis, and tenosynovitis have received insufficient attention. Therefore, this study evaluated the patterns of bone erosion, BME, synovitis, and tenosynovitis, and calculated the RA-MRI score (RAMRIS) of patients with RA at the carpal and metacarpophalangeal (MCP) joints using MRI.

methodsMRI datasets from 43 RA patients were analyzed. All patients had undergone MRI of one wrist. In addition, 36 patients had MCP joint images taken, and three had also received MRI of the contralateral wrist and MCP joints. The MR images were evaluated for bone erosion, BME, and synovitis in consensus by two blinded readers according to the Outcome Measures in Rheumatology Clinical Trials (OMERACT) RAMRIS. The MRI-detected tenosynovitis was evaluated based on Haavardsholm's tenosynovitis score.

resultsThe capitate, lunate, triquetrum, and hamate bones were the most common sites of erosion and BME and showed the highest RAMRIS erosion and BME scores. Moreover, MRI-detected tenosynovitis was present in 78.3% of all patients with RA, and the extensor compartment 4 and flexor digitorum profundus and superficialis were frequently affected.

conclusionThis study identified the distribution and prevalence of MRI-detected bone erosion, BME, synovitis, and tenosynovitis of the wrist and MCP joints in RA patients. The patterns of the MRI-detected abnormalities may help to select sites for the application of MRI protocols in clinical trials and practice.

Indexed as

Magnetic Resonance ImagingAdultAgedArthritis, RheumatoidBone MarrowEdemaFemaleHumansMaleMetacarpophalangeal JointMiddle AgedRepublic of KoreaRetrospective StudiesSynovitisTenosynovitisWrist JointArthritis, rheumatoidMagnetic resonance imagingSynovitisTenosynovitis

Identifiers

PMID29166759
PMCPMC6506727
OpenAlexW2768569559

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.