Evidence map›Paper›PMID 29166585›Full record

ArticleImmunity2017

Brain, Immunity, Gut: "BIG" Links between Pregnancy and Autism.

Myka L Estes, A Kimberley McAllister

Abstract readComment
In one paragraph

Article in Immunity, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
  4. Gut-X axis.iMeta · 2025
    Review
  5. Article
  6. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Myka L EstesCenter for Neuroscience, University of California Davis, One Shields Avenue, Davis, CA 95616, USA.
A Kimberley McAllisterCenter for Neuroscience, University of California Davis, One Shields Avenue, Davis, CA 95616, USA. Electronic address: kmcallister@ucdavis.edu.

Funding

UC Davis Conte Center: Neuroimmune Mechanisms of Psychiatric DisordersP50MH106438 · NIMH · UNIVERSITY OF CALIFORNIA AT DAVIS · PI HANKS, TIMOTHY D. · 2015 to 2025
$26.1M
Immune Molecules in Early Postnatal Nervous System DevelopmentR01NS060125 · NINDS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI MCALLISTER, A KIMBERLEY · 2010 to 2019
$3.3M
NIMH NIH HHS P50 MH106438NINDS NIH HHS R01 NS060125
6 · The paper itself

Abstract

Although dysregulation of brain, immune, and gut physiology during pregnancy have each been implicated in neuropsychiatric disorders, whether and how these presumably distinct systems are linked to cause disease is unclear. Kim et al. (2017) and Shin Yim et al. (2017) identify a pathway to explain how these aspects of our physiology are deeply and inextricably connected.

Indexed as

Autistic DisorderAnimalsBacteriaBrainMicePregnancy

Identifiers

PMID29166585
PMCPMC10088436

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.