Evidence map›Paper›PMID 29166543›Full record

Observational studyClinical cardiology2017

Transcatheter or surgical aortic valve replacement in patients with advanced kidney disease: A propensity score-matched analysis.

Rajkumar Doshi, Jay Shah, Vaibhav Patel, Varun Jauhar, Perwaiz Meraj

Open access · bronzeAbstract readComparative StudyObservational Study
In one paragraph

Observational study in Clinical cardiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 33 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Rajkumar DoshiDepartment of Cardiology, North Shore University Hospital, Northwell Health, Manhasset, New York.ORCID http://orcid.org/0000-0002-5618-2750
Jay ShahDepartment of Internal Medicine, Mercy Saint Vincent Hospital, University of Toledo, Toledo, Ohio.
Vaibhav PatelDepartment of Cardiology, North Shore University Hospital, Northwell Health, Manhasset, New York.
Varun JauharDepartment of Cardiology, North Shore University Hospital, Northwell Health, Manhasset, New York.
Perwaiz MerajDepartment of Cardiology, North Shore University Hospital, Northwell Health, Manhasset, New York.
Northwell Health · USMercy St. Vincent Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTranscatheter aortic valve replacement (TAVR) is an alternative for surgically inoperable patients with severe aortic stenosis. Advanced kidney disease may significantly affect outcomes in patients treated with TAVR and surgical aortic valve replacement (SAVR). HYPOTHESIS: TAVR is associated with better in-hospital outcomes compared with SAVR in patients with advanced kidney disease.

methodsWe identified our sample from the National Inpatient Sample between 2012 and 2014, using International Classification of Diseases, Ninth Revision, Clinical Modification codes. We included patients with chronic kidney disease stages IV and V and end-stage renal disease as advanced kidney disease patients. We excluded patients with acute kidney injury on admission and patients on dialysis.

resultsAfter propensity matching, 2485 patients were included in each group. The primary outcome of in-hospital mortality (12.9% vs 6.2%; P < 0.01) was higher with SAVR as compared with TAVR. Patients who underwent SAVR reported higher acute kidney injury (50.3% vs 33%; P < 0.01) and dialysis requirements (26.8% vs 20.1%; P < 0.01). Other secondary outcomes including blood transfusion, atrial fibrillation, iatrogenic cardiac complications, pericardial complications, perioperative stroke, perioperative infections, and postoperative shock were more common with SAVR. With SAVR, the length of hospitalization and hospitalization costs were significantly higher; however, permanent pacemaker placement was more common with TAVR compared with SAVR.

conclusionsIn patients with advanced kidney disease, SAVR was associated with higher mortality and higher periprocedural complications, as compared with TAVR. Thus, benefits of TAVR could be extended in patients with advanced kidney disease who cannot undergo surgery.

Indexed as

Heart Valve Prosthesis ImplantationTranscatheter Aortic Valve ReplacementAgedAged, 80 and overAortic ValveAortic Valve StenosisChi-Square DistributionCost-Benefit AnalysisDatabases, FactualFemaleHospital CostsHospital MortalityHumansKidney Failure, ChronicLength of StayLogistic ModelsAcute Kidney InjuryChronic Kidney DiseaseIn-hospital MortalitySurgical Aortic Valve ReplacementTransaortic Valve Replacement

Identifiers

PMID29166543
PMCPMC6490436
OpenAlexW2768809638

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.