Evidence map›Paper›PMID 29166322›Full record

ReviewMedicine and science in sports and exercise2018

Biological/Genetic Regulation of Physical Activity Level: Consensus from GenBioPAC.

J Timothy Lightfoot, Eco J C DE Geus, Frank W Booth, Molly S Bray, Marcel DEN Hoed, Jaakko Kaprio, Scott A Kelly, Daniel Pomp, Michael C Saul, Martine A Thomis and 2 more

Open access · greenAbstract readReviewConsensus Statement
In one paragraph

Review in Medicine and science in sports and exercise, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed, 3 pooled it
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 3 syntheses or guidelines pooled it, 112 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Genetic variants related to physical activity or sedentary behaviour: a systematic review.The international journal of behavioral nutrition and physical activity · 2021
    Pooled it
  4. Article
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  9. Review
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  13. Genetic confounding in the association of early motor development with childhood and adolescent exercise behavior.The international journal of behavioral nutrition and physical activity · 2024
    Article
  14. Estrogen-mediated individual differences in female rat voluntary running behavior.Journal of applied physiology (Bethesda, Md. : 1985) · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 8 institutions in 5 countries.

J Timothy LightfootDepartment of Health and Kinesiology, Texas A&M University, College Station, TX.
Eco J C DE GeusDepartment of Health and Kinesiology, Texas A&M University, College Station, TX.
Frank W BoothDepartment of Health and Kinesiology, Texas A&M University, College Station, TX.
Molly S BrayDepartment of Health and Kinesiology, Texas A&M University, College Station, TX.
Marcel DEN HoedDepartment of Health and Kinesiology, Texas A&M University, College Station, TX.
Jaakko KaprioDepartment of Health and Kinesiology, Texas A&M University, College Station, TX.
Scott A KellyDepartment of Health and Kinesiology, Texas A&M University, College Station, TX.
Daniel PompDepartment of Health and Kinesiology, Texas A&M University, College Station, TX.
Michael C SaulDepartment of Health and Kinesiology, Texas A&M University, College Station, TX.
Martine A ThomisDepartment of Health and Kinesiology, Texas A&M University, College Station, TX.
Theodore GarlandDepartment of Health and Kinesiology, Texas A&M University, College Station, TX.
Claude BouchardDepartment of Health and Kinesiology, Texas A&M University, College Station, TX.
Texas A&M University · USInstitute for Molecular Medicine Finland · FIPennington Biomedical Research Center · USUniversity of California, Riverside · USUniversity of Illinois Urbana-Champaign · USUniversity of Missouri · USUppsala University · SEVrije Universiteit Amsterdam · NL

Funding

Beyond GWAS of insulin resistance: An integrated approach to translate genetic association to functionR01DK106236 · NIDDK · STANFORD UNIVERSITY · PI KNOWLES, JOSHUA WILEY · 2016 to 2020
$2.4M
Early-life effects on adult physical activityR21HD084856 · NICHD · UNIVERSITY OF CALIFORNIA RIVERSIDE · PI GARLAND, THEODORE, SALTZMAN, WENDY · 2015 to 2016
$389k
NICHD NIH HHS R21 HD084856NIDDK NIH HHS R01 DK106236
6 · The paper itself

Abstract

purposePhysical activity unquestionably maintains and improves health; however, physical activity levels globally are low and not rising despite all the resources devoted to this goal. Attention in both the research literature and the public policy domain has focused on social-behavioral factors; however, a growing body of literature suggests that biological determinants play a significant role in regulating physical activity levels. For instance, physical activity level, measured in various manners, has a genetic component in both humans and nonhuman animal models. This consensus article, developed as a result of an American College of Sports Medicine-sponsored round table, provides a brief review of the theoretical concepts and existing literature that supports a significant role of genetic and other biological factors in the regulation of physical activity.

conclusionsFuture research on physical activity regulation should incorporate genetics and other biological determinants of physical activity instead of a sole reliance on social and other environmental determinants.

Indexed as

ExerciseHealth BehaviorBiologyEnvironmentGeneticsHumansSocieties, MedicalSports Medicine

Identifiers

PMID29166322
PMCPMC6481631
OpenAlexW2770967155

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.