ReviewNicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco2019
Oral Contraceptives and Cigarette Smoking: A Review of the Literature and Future Directions.
Review in Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 42 citations in OpenAlex.
- Feasibility and acceptability of testing a menstrual-cycle timed smoking cessation intervention for women of reproductive age (Project Phase): Results of a pilot randomized control trial.Addictive behaviors · 2022Trial
- We must look beyond primary reinforcement to understand nicotine use in women.Frontiers in neuroendocrinology · 2026Review
- Contraceptive hormone ethinyl estradiol but not levonorgestrel modulates the role of reinforcer-enhancement in nicotine self-administration in ovary-intact female Sprague-Dawley rats.Neuropharmacology · 2025Article
- Smoking Cessation in Black Adults: Differences by Sex and Age.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2025Article
- Oral contraceptive use and its sociocultural determinants in Iranian women: a secondary cross-sectional analysis from the PARS cohort study.Contraception and reproductive medicine · 2025Article
- Electronic nicotine delivery systems (ENDS) use across the menstrual cycle and oral contraceptive regimen: A proof-of-concept intensive longitudinal study.Drug and alcohol dependence reports · 2025Article
- A protocol for modifying progesterone to increase postpartum cigarette smoking abstinence and reduce secondhand smoke exposure in infants.Contemporary clinical trials communications · 2024Article
- Acceptability of Hormonal Contraceptives as a Smoking Cessation Aid for Women of Reproductive Age: A Web-Based Cross-Sectional Survey.Women's health reports (New Rochelle, N.Y.) · 2024Article
- Smoking-diseases correlation database: comprehensive analysis of the correlation between smoking and 422 diseases based on NHANES 2013-2018.Frontiers in public health · 2024Article
- Article
- Feasibility of remotely assessing hormonal contraceptive use and smoking-related symptomatology: Evidence from a preliminary prospective cohort study.Drug and alcohol dependence reports · 2023Article
- The importance of translationally evaluating steroid hormone contributions to substance use.Frontiers in neuroendocrinology · 2023Review
- Perinatal Psychoactive Substances Use: A Rising Perinatal Mental Health Concern.Journal of clinical medicine · 2023Review
- Impact of the natural hormonal milieu on ventral striatal responses to appetitive cigarette smoking cues: A prospective longitudinal study.Drug and alcohol dependence reports · 2022Article
- The association between hormonal contraceptive use and smoking, negative affect, and cessation attempts in college females.Drug and alcohol dependence reports · 2022Article
- Update on Management of Cardiovascular Diseases in Women.Journal of clinical medicine · 2022Review
- No Differences in Value-Based Decision-Making Due to Use of Oral Contraceptives.Frontiers in endocrinology · 2022Article
- Administration of Exogenous Hormones and the Implications for Cigarette Smoking-Related Behaviors.Current psychiatry reports · 2020Review
- Subjective response to intranasal nicotine administration in oral contraceptive users and naturally-cycling women.Addictive behaviors · 2019Article
- Commentary on Tosun et al. (2019): Dynamic changes in sex hormones and smoking cessation.Addiction (Abingdon, England) · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 4 institutions in 1 country.
Funding
Abstract
introductionEvidence continues to mount indicating that endogenous sex hormones (eg, progesterone and estradiol) play a significant role in smoking-related outcomes. Although approximately one out of four premenopausal smokers use oral contraceptives (OCs), which significantly alter progesterone and estradiol levels, relatively little is known about how OCs may influence smoking-related outcomes. Thus, the goal of this review article is to describe the state of the literature and offer recommendations for future directions.
methodsIn March 2017, we searched seven databases, with a restriction to articles written in English, using the following keywords: nicotine, smoker(s), smoking, tobacco, cigarettes, abstinence, withdrawal, and craving(s). We did not restrict on the publication date, type, or study design.
resultsA total of 13 studies were identified. Three studies indicated faster nicotine metabolism in OC users compared to nonusers. Five of six laboratory studies that examined physiological stress response noted heightened response in OC users compared to nonusers. Three studies examined cessation-related symptomatology (eg, craving) with mixed results. One cross-sectional study observed greater odds of current smoking among OC users, and no studies have explored the relationship between OC use and cessation outcomes.
conclusionsRelatively few studies were identified on the role of OCs in smoking-related outcomes. Future work could explore the relationship between OC use and mood, stress, weight gain, and brain function/connectivity, as well as cessation outcomes. Understanding the role of OC use in these areas may lead to the development of novel smoking cessation interventions for premenopausal women. IMPLICATIONS: This is the first review of the relationship between oral contraceptives (OCs) and smoking-related outcomes. The existing literature suggests that the use of OCs is related to increased nicotine metabolism and physiological stress response. However, the relationship between OC use and smoking-related symptoms (eg, craving) is mixed. Further, no published data were available on OC use and smoking cessation outcomes. Therefore, we recommend additional research be conducted to characterize the relationship between OC use and smoking cessation outcomes, perhaps as a function of the effect of OC use on mood, stress, weight gain, and brain function/connectivity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.