Evidence map›Paper›PMID 29165655›Full record

ArticleNucleic acids research2018

Expression Atlas: gene and protein expression across multiple studies and organisms.

Irene Papatheodorou, Nuno A Fonseca, Maria Keays, Y Amy Tang, Elisabet Barrera, Wojciech Bazant, Melissa Burke, Anja Füllgrabe, Alfonso Muñoz-Pomer Fuentes, Nancy George and 12 more

Open access · goldAbstract read
In one paragraph

Article in Nucleic acids research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 240 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
240citing papers in PubMed, 4 pooled it
23.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

240 citing papers in PubMed, 4 syntheses or guidelines pooled it, 452 citations in OpenAlex.

  1. IBDTransDB: a manually curated transcriptomic database for inflammatory bowel disease.Database : the journal of biological databases and curation · 2024
    Pooled it
  2. Pooled it
  3. The protein interaction networks of mucolipins and two-pore channels.Biochimica et biophysica acta. Molecular cell research · 2019
    Pooled it
  4. Pooled it
  5. Trial
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Interpretability-guided RNA NCommunications biology · 2025
    Article
  18. Linking individual fitness to the evolution of cognition.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025
    Review
  19. Article
  20. Article

180 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 2 institutions in 2 countries.

Irene PapatheodorouEuropean Molecular Biology Laboratory, European Bioinformatics Institute, EMBL-EBI, Hinxton, UK.
Nuno A FonsecaEuropean Molecular Biology Laboratory, European Bioinformatics Institute, EMBL-EBI, Hinxton, UK.
Maria KeaysEuropean Molecular Biology Laboratory, European Bioinformatics Institute, EMBL-EBI, Hinxton, UK.
Y Amy TangEuropean Molecular Biology Laboratory, European Bioinformatics Institute, EMBL-EBI, Hinxton, UK.
Elisabet BarreraEuropean Molecular Biology Laboratory, European Bioinformatics Institute, EMBL-EBI, Hinxton, UK.
Wojciech BazantEuropean Molecular Biology Laboratory, European Bioinformatics Institute, EMBL-EBI, Hinxton, UK.
Melissa BurkeEuropean Molecular Biology Laboratory, European Bioinformatics Institute, EMBL-EBI, Hinxton, UK.
Anja FüllgrabeEuropean Molecular Biology Laboratory, European Bioinformatics Institute, EMBL-EBI, Hinxton, UK.
Alfonso Muñoz-Pomer FuentesEuropean Molecular Biology Laboratory, European Bioinformatics Institute, EMBL-EBI, Hinxton, UK.
Nancy GeorgeEuropean Molecular Biology Laboratory, European Bioinformatics Institute, EMBL-EBI, Hinxton, UK.
Laura HuertaEuropean Molecular Biology Laboratory, European Bioinformatics Institute, EMBL-EBI, Hinxton, UK.
Satu KoskinenEuropean Molecular Biology Laboratory, European Bioinformatics Institute, EMBL-EBI, Hinxton, UK.
Suhaib MohammedEuropean Molecular Biology Laboratory, European Bioinformatics Institute, EMBL-EBI, Hinxton, UK.
Matthew GenizaOregon State University, Corvallis, USA.
Justin PreeceOregon State University, Corvallis, USA.
Pankaj JaiswalOregon State University, Corvallis, USA.
Andrew F JarnuczakEuropean Molecular Biology Laboratory, European Bioinformatics Institute, EMBL-EBI, Hinxton, UK.
Wolfgang HuberEuropean Molecular Biology Laboratory, European Bioinformatics Institute, EMBL-EBI, Hinxton, UK.
Oliver StegleEuropean Molecular Biology Laboratory, European Bioinformatics Institute, EMBL-EBI, Hinxton, UK.
Juan Antonio VizcainoEuropean Molecular Biology Laboratory, European Bioinformatics Institute, EMBL-EBI, Hinxton, UK.
Alvis BrazmaEuropean Molecular Biology Laboratory, European Bioinformatics Institute, EMBL-EBI, Hinxton, UK.
Robert PetryszakEuropean Molecular Biology Laboratory, European Bioinformatics Institute, EMBL-EBI, Hinxton, UK.
European Bioinformatics Institute · GBOregon State University · US

Funding

Wellcome Trust 108437/Z/15/ZWellcome Trust WT101477MA
6 · The paper itself

Abstract

Expression Atlas (http://www.ebi.ac.uk/gxa) is an added value database that provides information about gene and protein expression in different species and contexts, such as tissue, developmental stage, disease or cell type. The available public and controlled access data sets from different sources are curated and re-analysed using standardized, open source pipelines and made available for queries, download and visualization. As of August 2017, Expression Atlas holds data from 3,126 studies across 33 different species, including 731 from plants. Data from large-scale RNA sequencing studies including Blueprint, PCAWG, ENCODE, GTEx and HipSci can be visualized next to each other. In Expression Atlas, users can query genes or gene-sets of interest and explore their expression across or within species, tissues, developmental stages in a constitutive or differential context, representing the effects of diseases, conditions or experimental interventions. All processed data matrices are available for direct download in tab-delimited format or as R-data. In addition to the web interface, data sets can now be searched and downloaded through the Expression Atlas R package. Novel features and visualizations include the on-the-fly analysis of gene set overlaps and the option to view gene co-expression in experiments investigating constitutive gene expression across tissues or other conditions.

Indexed as

Databases, GeneticAnimalsGene Expression ProfilingHumansMammalsOligonucleotide Array Sequence AnalysisPlantsProteomicsSequence Analysis, RNASpecies SpecificityUser-Computer Interface

Identifiers

PMID29165655
PMCPMC5753389
OpenAlexW2769591387

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.