Evidence map›Paper›PMID 29165368›Full record

ReviewViruses2017

Human Protoparvoviruses.

Elina Väisänen, Yu Fu, Klaus Hedman, Maria Söderlund-Venermo

Abstract readReview
In one paragraph

Review in Viruses, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Lack of molecular evidence of fecal-borne viruses in capybaras from São Paulo state, Brazil, 2018-2020: a minor public health issue.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2023
    Article
  11. Review
  12. Best of most possible worlds: Hybrid gene therapy vectors based on parvoviruses and heterologous viruses.Molecular therapy : the journal of the American Society of Gene Therapy · 2021
    Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Newly detected DNA viruses in juvenile nasopharyngeal angiofibroma (JNA) and oral and oropharyngeal squamous cell carcinoma (OSCC/OPSCC).European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2019
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Elina VäisänenDepartment of Virology, University of Helsinki, Helsinki 00290, Finland. elina.vaisanen@helsinki.fi.
Yu FuDepartment of Virology, University of Helsinki, Helsinki 00290, Finland. yu.fu@helsinki.fi.
Klaus HedmanDepartment of Virology, University of Helsinki, Helsinki 00290, Finland. klaus.hedman@helsinki.fi.
Maria Söderlund-VenermoDepartment of Virology, University of Helsinki, Helsinki 00290, Finland. maria.soderlund-venermo@helsinki.fi.ORCID 0000-0002-4582-8317

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Next-generation sequencing and metagenomics have revolutionized the discovery of novel viruses. In recent years, three novel protoparvoviruses have been discovered in fecal samples of humans: bufavirus (BuV) in 2012, tusavirus (TuV) in 2014, and cutavirus (CuV) in 2016. BuV has since been studied the most, disclosing three genotypes that also represent serotypes. Besides one nasal sample, BuV DNA has been found exclusively in diarrheal feces, but not in non-diarrheal feces, suggesting a causal relationship. According to both geno- and seroprevalences, BuV appears to be the most common of the three novel protoparvoviruses, whereas TuV DNA has been found in only a single fecal sample, with antibody detection being equally rare. Moreover, the TuV sequence is closer to those of non-human protoparvoviruses, and so the evidence of TuV being a human virus is thus far insufficient. Interestingly, besides in feces, CuV has also been detected in skin biopsies of patients with cutaneous T-cell lymphoma and a patient with melanoma, while all other skin samples have tested PCR negative. Even if preliminary disease associations exist, the full etiological roles of these viruses in human disease are yet to be resolved.

Indexed as

Communicable Diseases, EmergingDiarrheaDNA, ViralFecesGastroenteritisGenome, ViralGenotypeHumansLymphoma, T-Cell, CutaneousMetagenomicsParvoviridaeParvoviridae InfectionsPhylogenyPolymerase Chain ReactionSequence Analysis, DNASerogroupDNA, Viralbufaviruscutaneous T-cell lymphomacutavirusdiscoveryemerging virusesepidemiologygastroenteritishuman protoparvovirustusavirus

Identifiers

PMID29165368
PMCPMC5707561

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.