Evidence map›Paper›PMID 29165352›Full record

ArticleInternational journal of molecular sciences2017

Antibody-Based Protective Immunity against Helminth Infections: Antibody Phage Display Derived Antibodies against BmR1 Antigen.

Anizah Rahumatullah, Izzati Zahidah Abdul Karim, Rahmah Noordin, Theam Soon Lim

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Construction of Naïve and Immune Human Fab Phage Display Library.Methods in molecular biology (Clifton, N.J.) · 2026
    Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. Applications of Recombinant Monoclonal Antibodies against Filarial Antigen Proteins.The American journal of tropical medicine and hygiene · 2020
    Article
  10. Development of an Antigen Detection ELISA for Bancroftian Filariasis UsingThe American journal of tropical medicine and hygiene · 2019
    Article
  11. Review
  12. Article
  13. Metazoan Parasite Vaccines: Present Status and Future Prospects.Frontiers in cellular and infection microbiology · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Anizah RahumatullahInstitute for Research in Molecular Medicine (INFORMM), Universiti Sains Malaysia, Minden 11800, Penang, Malaysia. anirah82@gmail.com.
Izzati Zahidah Abdul KarimInstitute for Research in Molecular Medicine (INFORMM), Universiti Sains Malaysia, Minden 11800, Penang, Malaysia. ezzati87@gmail.com.
Rahmah NoordinInstitute for Research in Molecular Medicine (INFORMM), Universiti Sains Malaysia, Minden 11800, Penang, Malaysia. rahmah8485@gmail.com.
Theam Soon LimInstitute for Research in Molecular Medicine (INFORMM), Universiti Sains Malaysia, Minden 11800, Penang, Malaysia. theamsoon@usm.my.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Helminth parasite infections are significantly impacting global health, with more than two billion infections worldwide with a high morbidity rate. The complex life cycle of the nematodes has made host immune response studies against these parasites extremely difficult. In this study, we utilized two phage antibody libraries; the immune and naïve library were used to identify single chain fragment variable (scFv) clones against a specific filarial antigen (B

Indexed as

ImmunityAmino AcidsAnimalsAntibodies, HelminthAntibodies, MonoclonalAntibody AffinityAntigens, HelminthCell Surface Display TechniquesComplementarity Determining RegionsEpitope MappingGene ExpressionHelminthiasisHelminthsHumansPeptide LibraryProtein BindingAmino AcidsAntibodies, HelminthAntibodies, MonoclonalAntigens, HelminthComplementarity Determining RegionsPeptide LibrarySingle-Chain AntibodiesBmR1immune librarymonoclonal antibodiesnaïve libraryphage displaysingle chain fragment variable (scFv)

Identifiers

PMID29165352
PMCPMC5713345

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.