Evidence map›Paper›PMID 29165248›Full record

ArticleeLife2017

Neuromodulatory connectivity defines the structure of a behavioral neural network.

Feici Diao, Amicia D Elliott, Fengqiu Diao, Sarav Shah, Benjamin H White

Abstract read
In one paragraph

Article in eLife, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Article
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  4. Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
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  15. Article
  16. Peptide-Liganded G Protein-Coupled Receptors as Neurotherapeutics.ACS pharmacology & translational science · 2020
    Review
  17. Article
  18. Two Splice Isoforms ofFrontiers in physiology · 2020
    Article
  19. TheFrontiers in neural circuits · 2020
    Review
  20. A spatially dynamic network underlies the generation of inspiratory behaviors.Proceedings of the National Academy of Sciences of the United States of America · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Feici DiaoLaboratory of Molecular Biology, National Institute of Mental Health, National Institutes of Health, Bethesda, United States.
Amicia D ElliottNational Institute of General Medical Sciences, National Institutes of Health, Bethesda, United States.
Fengqiu DiaoLaboratory of Molecular Biology, National Institute of Mental Health, National Institutes of Health, Bethesda, United States.
Sarav ShahLaboratory of Molecular Biology, National Institute of Mental Health, National Institutes of Health, Bethesda, United States.
Benjamin H WhiteLaboratory of Molecular Biology, National Institute of Mental Health, National Institutes of Health, Bethesda, United States.ORCID http://orcid.org/0000-0003-0612-8075

Funding

Identifying Neural Substrates of Behavior in Drosophila MelanogasterZIAMH002800 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI WHITE, BENJAMIN H · 2009 to 2025
$29.2M
Resource Component: Acquisition, maintenance and distribution of Drosophila stocksP40OD018537 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI KEVIN R COOK, THOMAS KAUFMAN · 2014 to 2026
$13.5M
Recording and Modeling Brain-wide Neuronal Activity of the Drosophila Pupal Ecdysis SequenceFI2GM117582 · NIGMS · U.S. NATIONAL INSTITUTE OF MENTAL HEALTH · PI ELLIOTT, AMICIA DEVIN · 2016 to 2016
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Intramural NIH HHS ZIA MH002800NIGMS NIH HHS FI2 GM117582NIH HHS P40 OD018537
6 · The paper itself

Abstract

Neural networks are typically defined by their synaptic connectivity, yet synaptic wiring diagrams often provide limited insight into network function. This is due partly to the importance of non-synaptic communication by neuromodulators, which can dynamically reconfigure circuit activity to alter its output. Here, we systematically map the patterns of neuromodulatory connectivity in a network that governs a developmentally critical behavioral sequence in

Indexed as

MoltingAnimalsBrainDrosophilaNerve NetPupabehaviorcalcium activityD. melanogasterecdysisneural circuitneuromodulationneuroscience

Identifiers

PMID29165248
PMCPMC5720592

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.