Evidence map›Paper›PMID 29165163›Full record

ArticleEnvironmental health and preventive medicine2017

The potential protective effect of Commelina nudiflora L. against carbon tetrachloride (CCl

Muhammad Dawood Shah, Urban J A D'Souza, Mohammad Iqbal

Open access · goldAbstract read
In one paragraph

Article in Environmental health and preventive medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
4.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 49 citations in OpenAlex.

  1. Hepatoprotective and Nephroprotective Effects ofInternational journal of molecular sciences · 2025
    Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Amelioration of CClScientific reports · 2023
    Article
  9. Chemical Composition and Biological Activity ofFoods (Basel, Switzerland) · 2023
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Review
  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Muhammad Dawood ShahBiotechnology Research Institute, Universiti Malaysia Sabah, Jalan UMS, 88400, Kota Kinabalu, Sabah, Malaysia.
Urban J A D'SouzaFaculty of Medicine and Health Science, Universiti Malaysia Sabah, Jalan UMS, 88400, Kota-Kinabalu, Sabah, Malaysia.
Mohammad IqbalBiotechnology Research Institute, Universiti Malaysia Sabah, Jalan UMS, 88400, Kota Kinabalu, Sabah, Malaysia. miqbal2k2008@hotmail.com.
Universiti of Malaysia Sabah · MY

Funding

Universiti Malaysia Sabah SBK0027-SKK-2012
6 · The paper itself

Abstract

backgroundThis study aims to assess the hepatoprotective potential of Commelina nudiflora against CCl

methodAntioxidant activities were determined. Phytochemical analysis was performed by gas chromatography mass spectrometry (GCMS). In the in vivo study, Sprague Dawley rats were pretreated with C. nudiflora (150, 300, and 450 mg kg body weight (b.wt.)) once daily for 14 days followed by two doses of CCl

resultsIn vitro studies have shown that the extract possessed strong antioxidant activity and has ability to scavenge 2,2-diphenyl-2-picrylhydrazyl-free radicals effectively. GCMS analysis of the C. nudiflora extract revealed the presence of various bioactive compounds. Administration of C. nudiflora significantly reduced the impact of CCl

conclusionThese findings exhibited the potential prospect of C. nudiflora as functional ingredients to prevent ROS-related liver damage.

Indexed as

AnimalsAntioxidantsCarbon TetrachlorideChemical and Drug Induced Liver InjuryCommelinaDose-Response Relationship, DrugGas Chromatography-Mass SpectrometryLiverMalePlant ExtractsProtective AgentsRandom AllocationRatsRats, Sprague-DawleyAntioxidantsCarbon TetrachloridePlant ExtractsProtective AgentsAcute liver injuryAntioxidant enzymesBioactive compoundsC. nudifloraHepatoprotectionImmunohistochemistry

Identifiers

PMID29165163
PMCPMC5664843
OpenAlexW2756422023

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.