ArticleEnvironmental health and preventive medicine2017
Increase in the prevalence of hypertension among adults exposed to the Great Chinese Famine during early life.
Article in Environmental health and preventive medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.
- Severe malnutrition or famine exposure in childhood and cardiometabolic non-communicable disease later in life: a systematic review.BMJ global health · 2021Pooled it
- Famine and blood pressure trajectories across 2 generations: a prospective cohort study.Clinical hypertension · 2026Article
- Diet in Pregnancy: A Review of Current Challenges and Recommendations. A British Nutrition Foundation Briefing Paper.Nutrition bulletin · 2025Review
- Sex-specific associations of prenatal Chinese famine exposure with cataract risk at age sixty: a cross-sectional study.BMC women's health · 2024Article
- Prenatal exposure to famine and the development of diabetes later in life: an age-period-cohort analysis of the China health and nutrition survey (CHNS) from 1997 to 2015.European journal of nutrition · 2023Article
- The Role of the Paraventricular-Coerulear Network on the Programming of Hypertension by Prenatal Undernutrition.International journal of molecular sciences · 2022Review
- Differential effect of prenatal exposure to the Great Ethiopian Famine (1983-85) on the risk of adulthood hypertension based on sex: a historical cohort study.BMC women's health · 2022Article
- Association between famine exposure in early life and risk of hospitalization for heart failure in adulthood.Frontiers in public health · 2022Article
- Individual and combined association analysis of famine exposure and serum uric acid with hypertension in the mid-aged and older adult: a population-based cross-sectional study.BMC cardiovascular disorders · 2021Article
- Combined Effect of Famine Exposure and Obesity Parameters on Hypertension in the Midaged and Older Adult: A Population-Based Cross-Sectional Study.BioMed research international · 2021Article
- Growing Burden of Hypertension in China: Causes, Challenges, and Opportunities.China CDC weekly · 2020Article
- Epidemic T2DM, early development and epigenetics: implications of the Chinese Famine.Nature reviews. Endocrinology · 2018Review
- Risk of Hyperglycemia and Diabetes after Early-Life Famine Exposure: A Cross-Sectional Survey in Northeastern China.International journal of environmental research and public health · 2018Article
- Correction to: Increase in the prevalence of hypertension among adults exposed to the great Chinese famine during early life.Environmental health and preventive medicine · 2018Article
Corrections and comments
- Erratum issued
Authors and funding
10 authors at 5 institutions in 4 countries.
Funding
Abstract
objectiveThis study aimed to assess the association between exposure to the Great Chinese Famine (1959-1961) during early life and hypertension in adulthood.
methodsFrom July to September 2009, 1224 eligible adults were recruited in a cross-sectional survey using a multi-stage stratified random sampling method in Chongqing China. A questionnaire was used to collect information of hypertension and sociodemographic factors. Participants were categorized as childhood, fetal, and none exposure to famine based on the date of birth.
resultsOf the sample, 12.3% reported having hypertension. The prevalence of hypertension varied by famine status: 11.9% in childhood exposure, 16.1% in fetal exposure, and 10.2% in non-exposure group. After adjusting for sociodemographic and lifestyle factors, compared with non-exposure group, fetal exposure group had an increased likelihood of having hypertension with odds ratio of 1.79 (95%CI 1.13-2.84). Although there was no significant gender and famine interaction, the positive association between famine exposure and hypertension was stronger among women than men.
conclusionFetal exposure to the Chinese famine may be associated with an increased risk of hypertension in adulthood in women [corrected].
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