SynthesisSports medicine (Auckland, N.Z.)2018
Lower Serum Zinc Concentration Despite Higher Dietary Zinc Intake in Athletes: A Systematic Review and Meta-analysis.
Synthesis in Sports medicine (Auckland, N.Z.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.
- The Role of Mineral and Trace Element Supplementation in Exercise and Athletic Performance: A Systematic Review.Nutrients · 2019Pooled it
- Trial
- Zinc Signaling in Acute Kidney Injury.Cells · 2026Review
- Nutritional considerations for athletes with diabetes: optimizing performance and glycemic control.Frontiers in nutrition · 2026Review
- Zinc Ameliorates Tripterygium Glycosides-Induced Reproductive Impairment in Male Rats by Regulating Zinc Homeostasis and Expression of Oxidative Stress-Related Genes.Biological trace element research · 2024Article
- Junior athletes' nutritional demands: a narrative review of consumption and prevalence of eating disorders.Frontiers in nutrition · 2024Review
- Considerations for the Consumption of Vitamin and Mineral Supplements in Athlete Populations.Sports medicine (Auckland, N.Z.) · 2023Review
- The relationship between dietary patterns and blood mineral concentration among children in Hunan Province of China.BMC public health · 2023Article
- Association between serum copper, zinc, and selenium concentrations and depressive symptoms in the US adult population, NHANES (2011-2016).BMC psychiatry · 2023Article
- Zinc-Deficient Diet Causes Imbalance in Zinc Homeostasis and Impaired Autophagy and Impairs Semen Quality in Mice.Biological trace element research · 2023Article
- Advancing athletic assessment by integrating conventional methods with cutting-edge biomedical technologies for comprehensive performance, wellness, and longevity insights.Frontiers in sports and active living · 2023Article
- Examining dietary behaviours, diet quality, motives and supplementation use in physically active individuals following vegetarian-based eating patterns.Nutrition bulletin · 2022Article
- Investigating the Role of Zinc in Atherosclerosis: A Review.Biomolecules · 2022Review
- Strategies for Therapeutic Amelioration of Aberrant Plasma ZnInternational journal of molecular sciences · 2022Review
- Influence of physical training on intracellular and extracellular zinc concentrations.Journal of the International Society of Sports Nutrition · 2022Article
- Manipulation of Dietary Intake on Changes in Circulating Testosterone Concentrations.Nutrients · 2021Review
- The Emerging Role of Nutraceuticals in Cardiovascular Calcification: Evidence from Preclinical and Clinical Studies.Nutrients · 2021Review
- Association between dietary zinc intake and abdominal aortic calcification in US adults.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundZinc is an essential trace element that has been implicated in numerous biological functions, including immunity, energy metabolism and antioxidative processes. Recent evaluations of the literature have provided evidence of significant acute changes in zinc metabolism following a bout of aerobic exercise.
objectiveThe aim of this study was to determine the zinc status of trained athletes compared with control populations, as described in cross-sectional studies.
designWe conducted a systematic literature search of the PubMed, Scopus, SPORTDiscus and Cochrane Library electronic databases from inception to 28 January 2016 to identify cross-sectional studies that determined the zinc status of athletes compared with a control population. Meta-analysis of the differences in serum zinc concentration and dietary zinc intake between groups were conducted.
resultsTwelve studies were included in the systematic review. Of the included studies, nine and eight studies provided sufficient data for the meta-analysis of serum zinc concentration and dietary zinc intake, respectively. Serum zinc concentration was significantly lower in athletes [- 0.93 μmol/L, 95% confidence interval (CI) - 1.62 to - 0.23] despite significantly higher dietary zinc intake compared with the control population (2.57 mg/day, 95% CI 0.97-4.16). Data on erythrocyte and urinary zinc from the included studies were insufficient for meta-analysis.
conclusionsDespite higher total dietary zinc intake, athletes generally have lower serum zinc concentration, which suggests that athletes have higher requirement of zinc than those who are physically inactive. Further investigations of zinc metabolism during exercise and dietary zinc requirement in active populations are needed to establish evidence-based recommendations.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.