Evidence map›Paper›PMID 29164520›Full record

ReviewEndocrine2018

Adrenal myelolipoma: a comprehensive review.

Ábel Decmann, Pál Perge, Miklós Tóth, Peter Igaz

Abstract readReview
PubMed Publisher
In one paragraph

Review in Endocrine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
73citing papers in PubMed, 1 pooled it
8.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

73 citing papers in PubMed, 1 synthesis or guideline pooled it, 143 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Adrenal myelolipoma with severe hemorrhage: a case report.Journal of surgical case reports · 2026
    Article
  4. Article
  5. Article
  6. Petroclival extra-adrenal myelolipoma: illustrative case.Journal of neurosurgery. Case lessons · 2025
    Article
  7. Article
  8. Review
  9. Article
  10. Adrenal lipoma formation via PI(3,4,5)PProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  11. Article
  12. Article
  13. Review
  14. A Rare Case of Catecholamine-Secreting Adrenal Myelolipoma.Journal of the ASEAN Federation of Endocrine Societies · 2025
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Observational
  20. Article

13 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Ábel Decmann2nd Department of Medicine, Semmelweis University, Szentkirályi str. 46., Budapest, 1088, Hungary.ORCID 0000-0002-4635-8644
Pál Perge2nd Department of Medicine, Semmelweis University, Szentkirályi str. 46., Budapest, 1088, Hungary.ORCID 0000-0002-0722-7684
Miklós Tóth2nd Department of Medicine, Semmelweis University, Szentkirályi str. 46., Budapest, 1088, Hungary.
Peter Igaz2nd Department of Medicine, Semmelweis University, Szentkirályi str. 46., Budapest, 1088, Hungary. igaz.peter@med.semmelweis-univ.hu.ORCID 0000-0003-2192-554X
Semmelweis University · HU

Funding

Hungarian National Research, Development and Innovation Office K115398
6 · The paper itself

Abstract

introductionAdrenal myelolipoma is an invariably benign neoplasm of the adrenal gland that is the second most common primary adrenal incidentaloma following adrenocortical adenomas. It is composed of elements of adipose tissue and extramedullary hematopoiesis. Hypotheses on stem cells and hormonal factors have been formulated regarding its pathogenesis that is still obscure. Despite its benign behavior, adrenal myelolipoma is clinically relevant as it might cause significant difficulties in the differential diagnosis of adrenal tumors.

methodsWe have reviewed 420 cases reported between 1957 and 2017 on adrenal myelolipoma retrieved from PubMed and Scopus databases and also 20 of our case series to provide a comprehensive analysis of their pathology, epidemiological and clinical features. RESULTS AND

conclusionsThe average age for its diagnosis was 51 years, and no gender difference was observed. The average size of tumors was 10.2 cm. Congenital adrenal hyperplasia was associated to 10% of all cases analyzed, while other adrenal hypersecretory disorders (cortisol, aldosterone) were found in 7.5% of cases. Computed tomography and magnetic resonance imaging can be reliably used for its differential diagnosis. If the diagnosis of an adrenal myelolipoma is unambiguous, and no associated symptoms or hormonal activity are established, surgical intervention is usually not necessary.

Indexed as

Adrenal Gland NeoplasmsMyelolipomaAdipose TissueAdrenal GlandsAdrenal Hyperplasia, CongenitalDiagnosis, DifferentialFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedTomography, X-Ray ComputedAdrenal myelolipomaCongenital adrenal hyperplasiaDifferential diagnosisManagement

Identifiers

PMID29164520
OpenAlexW2770637225

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.