Observational studyEuropean journal of orthopaedic surgery & traumatology : orthopedie traumatologie2018
C-reactive protein levels for early detection of early postoperative complications after proximal femoral fracture surgery.
Observational study in European journal of orthopaedic surgery & traumatology : orthopedie traumatologie, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 10 citations in OpenAlex.
- Article
- Impact of preoperative carbohydrate loading on postoperative course and morbidity in debulking surgery for epithelial ovarian cancer.Experimental and therapeutic medicine · 2024Article
- Medial femoral circumflex artery pseudoaneurysm following intramedullary nailing for intertrochanteric fracture.Trauma case reports · 2022Article
- Predicting the Exception-CRP and Primary Hip Arthroplasty.Journal of clinical medicine · 2021Article
- Huge Pseudoaneurysm of the Femoral Artery after Internal Fixation of Femoral Trochanteric Fracture.Case reports in orthopedics · 2018Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
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Abstract
introductionWe have studied the early C-reactive protein (CRP) kinetics after proximal femoral fracture (PFF) surgery and defined a chart of CRP threshold values beyond which early postoperative complications are likely. MATERIALS AND
methodsWe have prospectively followed up a 42-patient cohort for surgical treatment by osteosynthesis or hip arthroplasty, and CRP was dosed at admission, on day 1, day 3, day 5 and then twice weekly for 30 days at the same time as a platelet count control of low molecular weight heparins. Then, we identified postoperative complications (medical complications like infections other than the surgical site, thromboembolic complications, death and surgical complications like surgical site infections, dislocation, haematoma) and established the evolutive profile of CRP in a 'complication' group and a 'no complication' group. We developed a threshold value model for complications detection from our results and compared with Chapman's 500/d formula (d being the postoperative day).
resultsCRP in the 'complication' group (20 patients) is on average 19 points higher than the 'no complication' group (22 patients) (p = 0.007). Our model, which corresponds to the formula CRP(d) = e DISCUSSION/
conclusionEarly postoperative CRP kinetics of PFF surgical patients can be modelled as a threshold value scale valid between day 1 and day 30. This can be an additional tool in the early detection of postoperative complications, if two CRP values are above the threshold values, without replacing the clinical examination, which remains the 'gold standard'. LEVEL OF EVIDENCE: Prospective observational study.
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