Evidence map›Paper›PMID 29164299›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2018

Comparison of

Lino M Sawicki, Julian Kirchner, Johannes Grueneisen, Verena Ruhlmann, Bahriye Aktas, Benedikt M Schaarschmidt, Michael Forsting, Ken Herrmann, Gerald Antoch, Lale Umutlu

Abstract read
PubMed Publisher
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 2 pooled it
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 55 citations in OpenAlex.

  1. Diagnostic performance of whole-body [European radiology · 2024
    Pooled it
  2. Pooled it
  3. Clinical PET/MR.Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer · 2026
    Review
  4. Review
  5. Review
  6. The use of PET/MRI in radiotherapy.Insights into imaging · 2024
    Review
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  8. Article
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  13. Article
  14. Article
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  18. Relative clinical utility of simultaneousThe Journal of international medical research · 2021
    Article
  19. Diagnostic efficiency of whole-bodyCancer imaging : the official publication of the International Cancer Imaging Society · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Lino M SawickiMedical Faculty, Department of Diagnostic and Interventional Radiology, University Dusseldorf, Moorenstrasse 5, D-40225, Dusseldorf, Germany. linomorris.sawicki@med.uni-duesseldorf.de.
Julian KirchnerMedical Faculty, Department of Diagnostic and Interventional Radiology, University Dusseldorf, Moorenstrasse 5, D-40225, Dusseldorf, Germany.
Johannes GrueneisenMedical Faculty, Department of Diagnostic and Interventional Radiology and Neuroradiology, University Duisburg-Essen, D-45147, Essen, Germany.
Verena RuhlmannMedical Faculty, Department of Nuclear Medicine, University Duisburg-Essen, D-45147, Essen, Germany.
Bahriye AktasMedical Faculty, Department of Obstetrics and Gynecology, University Duisburg-Essen, D-45147, Essen, Germany.
Benedikt M SchaarschmidtMedical Faculty, Department of Diagnostic and Interventional Radiology, University Dusseldorf, Moorenstrasse 5, D-40225, Dusseldorf, Germany.
Michael ForstingMedical Faculty, Department of Diagnostic and Interventional Radiology and Neuroradiology, University Duisburg-Essen, D-45147, Essen, Germany.
Ken HerrmannMedical Faculty, Department of Nuclear Medicine, University Duisburg-Essen, D-45147, Essen, Germany.
Gerald AntochMedical Faculty, Department of Diagnostic and Interventional Radiology, University Dusseldorf, Moorenstrasse 5, D-40225, Dusseldorf, Germany.
Lale UmutluMedical Faculty, Department of Diagnostic and Interventional Radiology and Neuroradiology, University Duisburg-Essen, D-45147, Essen, Germany.
University of Duisburg-Essen · DEHeinrich Heine University Düsseldorf · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the diagnostic performance of

methodsSeventy-one consecutive women (54 ± 13 years, range: 25-80 years) with suspected recurrence of cervical (32), ovarian (26), endometrial (7), vulvar (4), and vaginal (2) cancer underwent PET/MRI including a diagnostic contrast-enhanced MRI protocol. PET/MRI and MRI datasets were separately evaluated regarding lesion count, localization, categorization (benign/malignant), and diagnostic confidence (3-point scale; 1-3) by two physicians. The reference standard was based on histopathology results and follow-up imaging. Diagnostic accuracy and proportions of malignant and benign lesions rated correctly were retrospectively compared using McNemar's chi

resultsFifty-five patients showed cancer recurrence. PET/MRI correctly identified more patients with cancer recurrence than MRI alone (100% vs. 83.6%, p < 0.01). In contrast to PET/MRI, MRI alone missed 4/15 patients with pelvic recurrence and miscategorized 8/40 patients with distant metastases as having local recurrence only. Based on the reference standard, 241 lesions were detected in the study cohort (181 malignant, 60 benign). While PET/MRI provided correct identification of 181/181 (100%) malignant lesions, MRI alone correctly identified 135/181 (74.6%) malignant lesions, which was significantly less compared to PET/MRI (p < 0.001). PET/MRI offered superior diagnostic accuracy (99.2% vs. 79.3%, p < 0.001) and diagnostic confidence in the categorization of malignant lesions compared with MRI alone (2.7 ± 0.5 vs. 2.4 ± 0.7, p < 0.001).

conclusionPET/MRI demonstrates excellent diagnostic performance and outperforms MRI alone for whole-body staging of women with suspected recurrent pelvic cancer, indicating potential changes in therapy management based on evaluation of local recurrence and distant metastatic spread.

Indexed as

Magnetic Resonance ImagingPositron-Emission TomographyAdultAgedAged, 80 and overFemaleFluorodeoxyglucose F18Follow-Up StudiesHumansMiddle AgedMultimodal ImagingNeoplasm Recurrence, LocalPelvic NeoplasmsRetrospective StudiesTomography, X-Ray ComputedWhole Body ImagingFluorodeoxyglucose F18CancerMRIPelvicPET/MRIRecurrent

Identifiers

PMID29164299
OpenAlexW2769648787

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.