Evidence map›Paper›PMID 29164298›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2018

Value of

Zhilei Lv, Jinshuo Fan, Juanjuan Xu, Feng Wu, Qi Huang, Mengfei Guo, Tingting Liao, Shuqing Liu, Xiaoli Lan, Shanshan Liao and 2 more

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06520189 (Value of F-18 FDG PET/CT for the Prediction of EGFR Mutation in Lung Cancer Patients), which is not on this map. Cited by 62 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed, 1 pooled it
6.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06520189 not yet recruitingnot on this mapstarted 2024, after this paper: background citation

Value of F-18 FDG PET/CT for the Prediction of EGFR Mutation in Lung Cancer Patients

TypeobservationalSponsorAssiut UniversityRan2024 to 2028Enrolled60ConditionsLung CancerArmsF-18 FDGPET/CT
3 · Its place in the literature

Who cites it

62 citing papers in PubMed, 1 synthesis or guideline pooled it, 99 citations in OpenAlex.

  1. CanBMJ open · 2021
    Pooled it
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  6. Article
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  9. Article
  10. ExplainableJournal of cancer research and clinical oncology · 2024
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  11. Article
  12. Article
  13. Amide proton transfer-weighted imaging and stretch-exponential model DWI basedCancer imaging : the official publication of the International Cancer Imaging Society · 2024
    Article
  14. Review
  15. Subregion-specificAmerican journal of nuclear medicine and molecular imaging · 2024
    Article
  16. Exploring the correlation between HER2 alterations andJournal of cancer research and clinical oncology · 2023
    Article
  17. Article
  18. Review
  19. Article
  20. Retrospective Analysis of the Predictive Value ofDiagnostics (Basel, Switzerland) · 2023
    Article

2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Zhilei LvKey Laboratory of Respiratory Diseases of the Ministry of health, Department of Respiratory and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefang Avenue, Wuhan, 430022, China.
Jinshuo FanKey Laboratory of Respiratory Diseases of the Ministry of health, Department of Respiratory and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefang Avenue, Wuhan, 430022, China.
Juanjuan XuKey Laboratory of Respiratory Diseases of the Ministry of health, Department of Respiratory and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefang Avenue, Wuhan, 430022, China.
Feng WuKey Laboratory of Respiratory Diseases of the Ministry of health, Department of Respiratory and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefang Avenue, Wuhan, 430022, China.
Qi HuangKey Laboratory of Respiratory Diseases of the Ministry of health, Department of Respiratory and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefang Avenue, Wuhan, 430022, China.
Mengfei GuoKey Laboratory of Respiratory Diseases of the Ministry of health, Department of Respiratory and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefang Avenue, Wuhan, 430022, China.
Tingting LiaoKey Laboratory of Respiratory Diseases of the Ministry of health, Department of Respiratory and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefang Avenue, Wuhan, 430022, China.
Shuqing LiuKey Laboratory of Respiratory Diseases of the Ministry of health, Department of Respiratory and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefang Avenue, Wuhan, 430022, China.
Xiaoli LanDepartment of Nuclear Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
Shanshan LiaoDepartment of Nuclear Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
Wei GengBiobank, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.
Yang JinKey Laboratory of Respiratory Diseases of the Ministry of health, Department of Respiratory and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefang Avenue, Wuhan, 430022, China. whuhjy@126.com.
Union Hospital · CNHuazhong University of Science and Technology · CN

Funding

Health and Planning Commission Fund of Hubei Province WJ2017M098Independent Innovation Research fund for Huazhong University of Science and Technology 2017KFYXJJ253National Natural Science Foundation of China 81572942Natural Science Foundation of Hubei Province 2014CFA057Science and Technology Support Program of Hubei Province YSF2015001294Wuhan Planning Project of Science and Technology 2014060101010036
6 · The paper itself

Abstract

purposeEpidermal growth factor receptor (EGFR) mutations and the anaplastic lymphoma kinase (ALK) rearrangement are the two most common druggable targets in non-small cell lung cancer (NSCLC). However, genetic testing is sometimes unavailable. Previous studies regarding the predictive role of

methodsWe retrospectively reviewed and included 849 NSCLC patients who were tested for EGFR mutations or ALK status and subjected to

resultsEGFR mutations were identified in 371 patients (45.9%). EGFR mutations were found more frequently in females, non-smokers, adenocarcinomas and stage I disease. Low pSUV

conclusionWe demonstrated that low pSUVmax is associated with mutant EGFR status and could be integrated with other clinical factors to enhance the discriminability on the EGFR mutation status in some NSCLC patients whose EGFR testing is unavailable.

Indexed as

Positron Emission Tomography Computed TomographyAdaptor Proteins, Signal TransducingAgedAnaplastic Lymphoma KinaseCarcinoma, Non-Small-Cell LungErbB ReceptorsFemaleFluorodeoxyglucose F18HumansLung NeoplasmsMaleMiddle AgedMutationRetrospective StudiesTomography, X-Ray ComputedAdaptor Proteins, Signal TransducingALK protein, humanAnaplastic Lymphoma KinaseEGFR protein, humanErbB ReceptorsFluorodeoxyglucose F18TAB3 protein, humanAnaplastic lymphoma kinaseEpidermal growth factor receptorMutationNon-small cell lung cancerPositron emission tomographyStandard uptake value

Identifiers

PMID29164298
PMCPMC5978918
OpenAlexW2770159367

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.