ReviewAdvances in medicine2017
A Systems Medicine Approach: Translating Emerging Science into Individualized Wellness.
Review in Advances in medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed.
- Intermittent time-restricted feeding recapitulates the physiological benefits of daily time-restricted feeding in male mice with chronic metabolic disease.Molecular metabolism · 2026Article
- A Functional Medicine Lens on Eating Disorders and Ultra-Processed Food Use Disorders: A Narrative Review.Integrative medicine (Encinitas, Calif.) · 2026Article
- Treating Metabolic Syndrome: P4 Medicine Meets Functional Medicine.Phenomics (Cham, Switzerland) · 2025Article
- Our Healing Journey: Restoring Connection, Finding Hope and Evolving Wellness.Integrative medicine (Encinitas, Calif.) · 2022Article
- Functional MedicineIntegrative medicine (Encinitas, Calif.) · 2022Article
- Personalized Lifestyle Intervention and Functional Evaluation Health Outcomes SurvEy: Presentation of the LIFEHOUSE Study Using N-of-One Tent-Umbrella-Bucket Design.Journal of personalized medicine · 2022Article
- Individual risk management strategy for SARS-CoV-2 infection: A step toward personalized healthcare.International immunopharmacology · 2021Article
- Deep learning in systems medicine.Briefings in bioinformatics · 2021Review
- Data Integration Challenges for Machine Learning in Precision Medicine.Frontiers in medicine · 2021Review
- Role of antioxidants and a nutrient rich diet in Alzheimer's disease.Open biology · 2020Review
- Systems Biology Meets Functional Medicine.Integrative medicine (Encinitas, Calif.) · 2019Article
- Clinical Applications of System Regulation Medicine.Open access Macedonian journal of medical sciences · 2019Review
- What is Evidence-Based Functional Medicine in the 21st Century?Integrative medicine (Encinitas, Calif.) · 2019Article
- The Natural Roots of Functional Medicine.Integrative medicine (Encinitas, Calif.) · 2018Article
- Cardiology Meets Personalized Lifestyle Medicine.Integrative medicine (Encinitas, Calif.) · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In today's aging society, more people are living with lifestyle-related noncommunicable diseases (NCDs) such as cardiovascular disease, type 2 diabetes, obesity, and cancer. Numerous opinion-leader organizations recommend lifestyle medicine as the first-line approach in NCD prevention and treatment. However, there is a strong need for a personalized approach as "one-size-fits-all" public health recommendations have been insufficient in addressing the interindividual differences in the diverse populations. Advancement in systems biology and the "omics" technologies has allowed comprehensive analysis of how complex biological systems are impacted upon external perturbations (e.g., nutrition and exercise), and therefore is gradually pushing personalized lifestyle medicine toward reality. Clinicians and healthcare practitioners have a unique opportunity in advocating lifestyle medicine because patients see them as a reliable source of advice. However, there are still numerous technical and logistic challenges to overcome before personal "big data" can be translated into actionable and clinically relevant solutions. Clinicians are also facing various issues prior to bringing personalized lifestyle medicine to their practice. Nevertheless, emerging ground-breaking research projects have given us a glimpse of how systems thinking and computational methods may lead to personalized health advice. It is important that all stakeholders work together to create the needed paradigm shift in healthcare before the rising epidemic of NCDs overwhelm the society, the economy, and the dated health system.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.