Evidence map›Paper›PMID 29164134›Full record

ReviewFrontiers in cardiovascular medicine2017

Cancer and Thrombotic Risk: The Platelet Paradigm.

Elizabeth C Lee, Scott J Cameron

Abstract readReview
In one paragraph

Review in Frontiers in cardiovascular medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Prognostic Value and Clinicopathologic Features of Platelet Distribution Width in Cancer: A Meta-Analysis.Medical science monitor : international medical journal of experimental and clinical research · 2018
    Pooled it
  2. Review
  3. Article
  4. Review
  5. Article
  6. Pro-Tumorigenic and Thrombotic Activities of Platelets in Lung Cancer.International journal of molecular sciences · 2023
    Review
  7. Review
  8. Article
  9. Review
  10. Article
  11. Heparin and Derivatives for Advanced Cell Therapies.International journal of molecular sciences · 2021
    Review
  12. Review
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Elizabeth C LeeAab Cardiovascular Research Institute, Rochester, NY, United States.
Scott J CameronAab Cardiovascular Research Institute, Rochester, NY, United States.

Funding

Platelet ERK5 regulates myocardial infarct expansionK08HL128856 · NHLBI · UNIVERSITY OF ROCHESTER · PI CAMERON, SCOTT JAMES · 2016 to 2020
$775k
NHLBI NIH HHS K08 HL128856NHLBI NIH HHS L30 HL120200
6 · The paper itself

Abstract

Hematologic malignancies and solid tumors increase the risk of venous and arterial thrombosis and contribute greatly to patient morbidity and mortality. Thrombosis occurs when the intricate balance of circulating antithrombotic and prothrombotic blood elements are disrupted. In recent years, the interplay between paraneoplastic cells and platelets has become apparent, with a change in platelet phenotype causing dysregulated platelet activity. This review discusses mechanism of thrombosis in cancer, evidence for using drug therapy, and exciting research efforts to understand and hopefully control aberrant thrombotic events in patients with cancer.

Indexed as

antiocoagulationcancer progressiondysregulated plateletsplatelet activationplatelet dysfunctionthrombosis

Identifiers

PMID29164134
PMCPMC5682001

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.