Evidence map›Paper›PMID 29164032›Full record

ReviewGlobal spine journal2017

Change in Function, Pain, and Quality of Life Following Structured Nonoperative Treatment in Patients With Degenerative Cervical Myelopathy: A Systematic Review.

Lindsay A Tetreault, John Rhee, Heidi Prather, Brian K Kwon, Jefferson R Wilson, Allan R Martin, Ian B Andersson, Anna H Dembek, Krystle T Pagarigan, Joseph R Dettori and 1 more

Abstract readReview
In one paragraph

Review in Global spine journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Conservative and newer drug treatment for degenerative cervical myelopathy.Journal of clinical orthopaedics and trauma · 2025
    Article
  6. Cervical kyphosis after posterior cervical laminectomy with and without fusion.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2024
    Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Lindsay A TetreaultToronto Western Hospital, University Health Network, Toronto, Ontario, Canada.
John RheeEmory University, Atlanta, GA, USA.
Heidi PratherWashington University, St Louis, MO, USA.
Brian K KwonVancouver General Hospital, Vancouver, British Columbia, Canada.
Jefferson R WilsonUniversity of Toronto, Toronto, Ontario, Canada.
Allan R MartinToronto Western Hospital, University Health Network, Toronto, Ontario, Canada.
Ian B AnderssonUniversity of Puget Sound, Tacoma, WA, USA.
Anna H DembekUniversity of Puget Sound, Tacoma, WA, USA.
Krystle T PagariganSpectrum Research, Inc, Tacoma, WA, USA.
Joseph R DettoriSpectrum Research, Inc, Tacoma, WA, USA.
Michael G FehlingsToronto Western Hospital, University Health Network, Toronto, Ontario, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STUDY

designSystematic review.

objectivesThe objective of this study was to conduct a systematic review to determine (1) change in function, pain, and quality of life following structured nonoperative treatment for degenerative cervical myelopathy (DCM); (2) variability of change in function, pain, and quality of life following different types of structured nonoperative treatment; (3) differences in outcomes observed between certain subgroups (eg, baseline severity score, duration of symptoms); and (4) negative outcomes and harms resulting from structured nonoperative treatment.

methodsA systematic search was conducted in Embase, PubMed, and the Cochrane Collaboration for articles published between January 1, 1950, and February 9, 2015. Studies were included if they evaluated outcomes following structured nonoperative treatment, including therapeutic exercise, manual therapy, cervical bracing, and/or traction. The quality of each study was evaluated using the Newcastle-Ottawa Scale, and strength of the overall body of evidence was rated using guidelines outlined by the Grading of Recommendation Assessment, Development and Evaluation Working Group.

resultsOf the 570 retrieved citations, 8 met inclusion criteria and were summarized in this review. Based on our results, there is very low evidence to suggest that structured nonoperative treatment for DCM results in either a positive or negative change in function as evaluated by the Japanese Orthopaedic Association score.

conclusionThere is a lack of evidence to determine the role of nonoperative treatment in patients with DCM. However, in the majority of studies, patients did not achieve clinically significant gains in function following structured nonoperative treatment. Furthermore, 23% to 54% of patients managed nonoperatively subsequently underwent surgical treatment.

Indexed as

cervical spondylotic myelopathydegenerative cervical myelopathynonoperative treatmentsystematic review

Identifiers

PMID29164032
PMCPMC5684835

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.