Evidence map›Paper›PMID 29163910›Full record

ArticleChemical science2017

Cholesterol-directed nanoparticle assemblies based on single amino acid peptide mutations activate cellular uptake and decrease tumor volume.

Shang Li, Rongfeng Zou, Yaoquan Tu, Junchen Wu, Markita P Landry

Open access · diamondAbstract read
In one paragraph

Article in Chemical science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 25 citations in OpenAlex.

  1. Peptide-based drugs in immunotherapy: current advances and future prospects.Medical oncology (Northwood, London, England) · 2025
    Review
  2. Article
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 4 countries.

Shang LiKey Laboratory for Advanced Materials & Institute of Fine Chemicals , School of Chemistry and Molecular Engineering , East China University of Science and Technology , Shanghai 200237 , China . Email: jcwu@ecust.edu.cn.
Rongfeng ZouKey Laboratory for Advanced Materials & Institute of Fine Chemicals , School of Chemistry and Molecular Engineering , East China University of Science and Technology , Shanghai 200237 , China . Email: jcwu@ecust.edu.cn.
Yaoquan TuDivision of Theoretical Chemistry and Biology , School of Biotechnology , KTH Royal Institute of Technology , SE-10691 Stockholm , Sweden.
Junchen WuKey Laboratory for Advanced Materials & Institute of Fine Chemicals , School of Chemistry and Molecular Engineering , East China University of Science and Technology , Shanghai 200237 , China . Email: jcwu@ecust.edu.cn.
Markita P LandryDepartment of Chemical and Bio-molecular Engineering , University of California Berkeley , 476 Stanley Hall , Berkeley , California 94720 , USA . Email: landry@berkeley.edu.ORCID 0000-0002-5832-8522
East China University of Science and Technology · CNLaboratoire de Biochimie Théorique · FRQB3 · US

Funding

Single-Molecule Imaging of Biological Trauma:Cytokine-Based Intracellular CommunicationR35GM128922 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI LANDRY, MARKITA · 2019 to 2023
$2.0M
NIGMS NIH HHS R35 GM128922
6 · The paper itself

Abstract

Peptide drugs have been difficult to translate into effective therapies due to their low

Identifiers

PMID29163910
PMCPMC5676250
OpenAlexW2754837091

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.