Evidence map›Paper›PMID 29163753›Full record

ArticleOxidative medicine and cellular longevity2017

Cytoprotective Effects of Citicoline and Homotaurine against Glutamate and High Glucose Neurotoxicity in Primary Cultured Retinal Cells.

Sergio Davinelli, Flavia Chiosi, Roberto Di Marco, Ciro Costagliola, Giovanni Scapagnini

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 34 citations in OpenAlex.

  1. Pyrroloquinoline Quinone and NADPharmaceuticals (Basel, Switzerland) · 2026
    Review
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  17. Observational
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  20. Citicoline Protects Auditory Hair Cells Against Neomycin-Induced Damage.Frontiers in cell and developmental biology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Sergio DavinelliDepartment of Medicine and Health Sciences "V. Tiberio", University of Molise, Campobasso, Italy.ORCID 0000-0003-2578-7199
Flavia ChiosiDepartment of Medicine and Health Sciences "V. Tiberio", University of Molise, Campobasso, Italy.
Roberto Di MarcoDepartment of Medicine and Health Sciences "V. Tiberio", University of Molise, Campobasso, Italy.
Ciro CostagliolaDepartment of Medicine and Health Sciences "V. Tiberio", University of Molise, Campobasso, Italy.ORCID 0000-0001-8477-6188
Giovanni ScapagniniDepartment of Medicine and Health Sciences "V. Tiberio", University of Molise, Campobasso, Italy.
University of Molise · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Citicoline and homotaurine are renowned compounds that exhibit potent neuroprotective activities through distinct molecular mechanisms. The present study was undertaken to demonstrate whether cotreatment with citicoline and homotaurine affects cell survival in primary retinal cultures under experimental conditions simulating retinal neurodegeneration. Primary cultures were obtained from the retina of fetal rats and exposed to citicoline plus homotaurine (100

Indexed as

Cells, CulturedCytidine Diphosphate CholineGlucoseGlutamic AcidNeurotoxicity SyndromesRetinaTaurineCytidine Diphosphate CholineGlucoseGlutamic AcidTaurinetramiprosate

Identifiers

PMID29163753
PMCPMC5661090
OpenAlexW2763572504

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.