ArticleFrontiers in plant science2017
Cultivar Diversity of Grape Skin Polyphenol Composition and Changes in Response to Drought Investigated by LC-MS Based Metabolomics.
Article in Frontiers in plant science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.
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Who cites it
36 citing papers in PubMed, 1 synthesis or guideline pooled it, 98 citations in OpenAlex.
- Meta-Analysis of the Effects of Foods and Derived Products Containing Ellagitannins and Anthocyanins on Cardiometabolic Biomarkers: Analysis of Factors Influencing Variability of the Individual Responses.International journal of molecular sciences · 2018Pooled it
- Comprehensive Analysis of Phytochemical Compounds in Seeds of Indigenous Grape Varieties Cultivated in Southeastern Anatolia: Fatty Acids, Tocopherols, Phytosterols, Vitamins, and Antioxidant Properties.Molecules (Basel, Switzerland) · 2026Article
- Highly dynamic metabolic response of grapevine to water deficits reveals an adaptability to a wide range of climatic conditions.Food chemistry: X · 2026Article
- Association Between Contrasting Water Regimes and Telomere Length Variation in Field-Grown Grapevines: An Integrated Physiological, Metabolomic and Molecular Approach.Plants (Basel, Switzerland) · 2026Article
- Differences in Non-Anthocyanin Phenolics and Antioxidant Capacity of 27 Red Grapevine Varieties Grown in Northern Portugal.Molecules (Basel, Switzerland) · 2025Article
- Polyphenols Bioactive Metabolites, and Their Anti-Biofilm and Neuroprotective Potential.Foods (Basel, Switzerland) · 2025Review
- Sustainable Foliar Applications to Improve Grapevine Responses to Drought, High Temperatures, and Salinity: Impacts on Physiology, Yields, and Berry Quality.Plants (Basel, Switzerland) · 2025Review
- Biowaste Valorization: The Wine Industry Case.Advances in biochemical engineering/biotechnology · 2025Review
- Exploration of the anthocyanin and proanthocyanidin profile of Greek red grape skins belonging to Vradiano, Limnio, and Kotsifali cultivars, analyzed by a novel LC-QTOF-MS/MS method.Phytochemical analysis : PCA · 2024Article
- Climate-Affected Australian Tropical Montane Cloud Forest Plants: Metabolomic Profiles, Isolated Phytochemicals, and Bioactivities.Plants (Basel, Switzerland) · 2024Review
- Applicability of metabolomics to improve sustainable grapevine production.Frontiers in molecular biosciences · 2024Review
- Color Characterization of Bordeaux Red Wines Produced without Added Sulfites.Foods (Basel, Switzerland) · 2023Article
- Terroir Influence on Polyphenol Metabolism from Grape Canes: A Spatial Metabolomic Study at Parcel Scale.Molecules (Basel, Switzerland) · 2023Article
- Comprehensive Microbiome and Metabolome Analyses Reveal the Medicinal Components ofPlants (Basel, Switzerland) · 2023Article
- An Optimized HPLC-DAD Methodology for the Determination of Anthocyanins in Grape Skins of Red Greek Winegrape Cultivars (Molecules (Basel, Switzerland) · 2022Article
- Expression Analyses in the Rachis Hint towards Major Cell Wall Modifications in Grape Clusters Showing Berry Shrivel Symptoms.Plants (Basel, Switzerland) · 2022Article
- A genome-wide association and prediction study in grapevine deciphers the genetic architecture of multiple traits and identifies genes under many new QTLs.G3 (Bethesda, Md.) · 2022Article
- Advances in Plant Metabolomics and Its Applications in Stress and Single-Cell Biology.International journal of molecular sciences · 2022Review
- Vine Irrigation through Two Shoot Densities in Flavonoid and Non-Flavonoid Compounds in 'Tempranillo' Grapes.Plants (Basel, Switzerland) · 2022Article
- Multi-Year Study of the Chemical and Sensory Effects of Microwave-Assisted Extraction of Musts and Stems in Cabernet Sauvignon, Merlot and Syrah Wines from the Central Coast of California.Molecules (Basel, Switzerland) · 2022Article
Corrections and comments
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Authors and funding
12 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Phenolic compounds represent a large family of plant secondary metabolites, essential for the quality of grape and wine and playing a major role in plant defense against biotic and abiotic stresses. Phenolic composition is genetically driven and greatly affected by environmental factors, including water stress. A major challenge for breeding of grapevine cultivars adapted to climate change and with high potential for wine-making is to dissect the complex plant metabolic response involved in adaptation mechanisms. A targeted metabolomics approach based on ultra high-performance liquid chromatography coupled to triple quadrupole mass spectrometry (UHPLC-QqQ-MS) analysis in the Multiple Reaction Monitoring (MRM) mode has been developed for high throughput profiling of the phenolic composition of grape skins. This method enables rapid, selective, and sensitive quantification of 96 phenolic compounds (anthocyanins, phenolic acids, stilbenoids, flavonols, dihydroflavonols, flavan-3-ol monomers, and oligomers…), and of the constitutive units of proanthocyanidins (i.e., condensed tannins), giving access to detailed polyphenol composition. It was applied on the skins of mature grape berries from a core-collection of 279
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Registered trials
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