Evidence map›Paper›PMID 29163488›Full record

ArticleFrontiers in immunology2017

Late-Onset Cryopyrin-Associated Periodic Syndromes Caused by Somatic NLRP3 Mosaicism-UK Single Center Experience.

Dorota M Rowczenio, Sónia Melo Gomes, Juan I Aróstegui, Anna Mensa-Vilaro, Ebun Omoyinmi, Hadija Trojer, Anna Baginska, Alberto Baroja-Mazo, Pablo Pelegrin, Sinisa Savic and 5 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
69citing papers in PubMed, 2 pooled it
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

69 citing papers in PubMed, 2 syntheses or guidelines pooled it, 146 citations in OpenAlex.

  1. Pooled it
  2. Guideline
  3. Trial
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Concomitant Systemic Autoinflammatory Diseases:Sultan Qaboos University medical journal · 2025
    Article
  16. SomaticFrontiers in pediatrics · 2025
    Article
  17. Review
  18. Article
  19. Review
  20. Review

9 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 6 institutions in 2 countries.

Dorota M RowczenioNational Amyloidosis Centre, University College London, London, United Kingdom.
Sónia Melo GomesGreat Ormond Street Institute of Child Health (ICH), University College London, London, United Kingdom.
Juan I ArósteguiDepartment of Immunology, Hospital Clinic-IDIBAPS, Barcelona, Spain.
Anna Mensa-VilaroDepartment of Immunology, Hospital Clinic-IDIBAPS, Barcelona, Spain.
Ebun OmoyinmiGreat Ormond Street Institute of Child Health (ICH), University College London, London, United Kingdom.
Hadija TrojerNational Amyloidosis Centre, University College London, London, United Kingdom.
Anna BaginskaNational Amyloidosis Centre, University College London, London, United Kingdom.
Alberto Baroja-MazoInflammation and Experimental Surgery Unit, Biomedical Research Institute of Murcia IMIB-Arrixaca, Clinical University Hospital Virgen de la Arrixaca, Murcia, Spain.
Pablo PelegrinInflammation and Experimental Surgery Unit, Biomedical Research Institute of Murcia IMIB-Arrixaca, Clinical University Hospital Virgen de la Arrixaca, Murcia, Spain.
Sinisa SavicNational Institute for Health Research-Leeds Musculoskeletal Biomedical Research Unit, Leeds Institute of Rheumatic and Musculoskeletal Medicine, Leeds, United Kingdom.
Thirusha LaneNational Amyloidosis Centre, University College London, London, United Kingdom.
Rene WilliamsNational Amyloidosis Centre, University College London, London, United Kingdom.
Paul BroganGreat Ormond Street Institute of Child Health (ICH), University College London, London, United Kingdom.
Helen J LachmannNational Amyloidosis Centre, University College London, London, United Kingdom.
Philip N HawkinsNational Amyloidosis Centre, University College London, London, United Kingdom.
University College London · GBInstituto Murciano de Investigación Biosanitaria · ESConsorci Institut D'Investigacions Biomediques August Pi I Sunyer · ESGreat Ormond Street Hospital · GBHospital Clínic de Barcelona · ESNIHR Leeds Musculoskeletal Biomedical Research Unit · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cryopyrin-associated periodic syndrome (CAPS) is caused by

Indexed as

AA amyloidosisASC aggregatescryopyrin-associated periodic syndromeIL-1βmutant alleleNLRP3 somatic mutation

Identifiers

PMID29163488
PMCPMC5671490
OpenAlexW2766050608

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.