Evidence map›Paper›PMID 29163483›Full record

ArticleFrontiers in immunology2017

CD4 T-Cell Dysregulation in Psoriatic Arthritis Reveals a Regulatory Role for IL-22.

Amara Ezeonyeji, Helen Baldwin, Milica Vukmanovic-Stejic, Michael R Ehrenstein

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Amara EzeonyejiCentre for Rheumatology, Division of Medicine, University College London, London, United Kingdom.
Helen BaldwinCentre for Rheumatology, Division of Medicine, University College London, London, United Kingdom.
Milica Vukmanovic-StejicDivision of Infection and Immunity, University College London, London, United Kingdom.
Michael R EhrensteinCentre for Rheumatology, Division of Medicine, University College London, London, United Kingdom.
University College London · GB

Funding

Versus Arthritis 19823
6 · The paper itself

Abstract

Dysregulation of interleukin-22 (IL-22) has been associated with autoimmune diseases but divergent effects upon inflammation have hampered efforts to define its contribution to pathogenesis. Here, we examined the role of IL-22 in patients with psoriatic arthritis (PsA). In the peripheral blood of PsA patients, there was a decrease in IL-22

Indexed as

anti-TNFIL-22interferon-gammanaïve T cellpsoriatic arthritis

Identifiers

PMID29163483
PMCPMC5666299
OpenAlexW2765427648

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.