Evidence map›Paper›PMID 29163476›Full record

ArticleFrontiers in immunology2017

Induction of Peripheral Tolerance in Ongoing Autoimmune Inflammation Requires Interleukin 27 Signaling in Dendritic Cells.

Rodolfo Thomé, Jason N Moore, Elisabeth R Mari, Javad Rasouli, Daniel Hwang, Satoshi Yoshimura, Bogoljub Ciric, Guang-Xian Zhang, Abdolmohamad M Rostami

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Protective effects of differentJournal of advanced research · 2022
    Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. IL-27 Regulated CD4Frontiers in immunology · 2020
    Article
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Rodolfo ThoméDepartment of Neurology, Jefferson Hospital for Neuroscience, Thomas Jefferson University, Philadelphia, PA, United States.
Jason N MooreDepartment of Neurology, Jefferson Hospital for Neuroscience, Thomas Jefferson University, Philadelphia, PA, United States.
Elisabeth R MariDepartment of Neurology, Jefferson Hospital for Neuroscience, Thomas Jefferson University, Philadelphia, PA, United States.
Javad RasouliDepartment of Neurology, Jefferson Hospital for Neuroscience, Thomas Jefferson University, Philadelphia, PA, United States.
Daniel HwangDepartment of Neurology, Jefferson Hospital for Neuroscience, Thomas Jefferson University, Philadelphia, PA, United States.
Satoshi YoshimuraDepartment of Neurology, Jefferson Hospital for Neuroscience, Thomas Jefferson University, Philadelphia, PA, United States.
Bogoljub CiricDepartment of Neurology, Jefferson Hospital for Neuroscience, Thomas Jefferson University, Philadelphia, PA, United States.
Guang-Xian ZhangDepartment of Neurology, Jefferson Hospital for Neuroscience, Thomas Jefferson University, Philadelphia, PA, United States.
Abdolmohamad M RostamiDepartment of Neurology, Jefferson Hospital for Neuroscience, Thomas Jefferson University, Philadelphia, PA, United States.
Jefferson Hospital for Neuroscience · USThomas Jefferson University · US

Funding

Mechanisms of GM-CSF effect in CNS autoimmune demyelinationR01AI124386 · NIAID · THOMAS JEFFERSON UNIVERSITY · PI ROSTAMI, A.M. · 2017 to 2021
$1.9M
The role of IL-27 in iv tolerance in EAER01AI106026 · NIAID · THOMAS JEFFERSON UNIVERSITY · PI ROSTAMI, A.M. · 2014 to 2018
$1.9M
NSCs produce a triply effective cocktail in the CNS for MS/EAE therapyR01NS075260 · NINDS · THOMAS JEFFERSON UNIVERSITY · PI ZHANG, GUANG-XIAN · 2012 to 2016
$1.5M
NIAID NIH HHS R01 AI106026NIAID NIH HHS R01 AI124386NINDS NIH HHS R01 NS075260
6 · The paper itself

Abstract

Peripheral tolerance to autoantigens is induced

Indexed as

dendritic cellsexperimental autoimmune encephalomyelitisimmunomodulationinterleukin 27tolerance

Identifiers

PMID29163476
PMCPMC5663690
OpenAlexW2765907853

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.